Serum or plasma concentration of human chorionic gonadotropin (hCG)
This test measures the amount of human chorionic gonadotropin (hCG), a hormone produced during pregnancy, in your blood or serum.
["Helps confirm pregnancy or detect early pregnancy loss."]
Key facts at a glance
- LOINC
- 77191-5
- Short code
- Deprecated HE4 SerPl EIA-sCnc
- Synonyms
- Deprecated HE4 SerPl EIA-sCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- eia
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Doctors order an hCG test to confirm pregnancy, especially when early symptoms like missed periods, nausea, or breast tenderness appear. It may also be used to monitor high-risk pregnancies, check for ectopic pregnancies, or evaluate fertility treatments. In some cases, it can help diagnose conditions like ovarian tumors or certain cancers.
What to Expect Before the Test
No special preparation is needed, but you may be asked to fast for 8–12 hours before the blood draw if your lab requires it. Wear comfortable clothing and plan to stay for the procedure, as it typically takes a few minutes. If you’re pregnant, inform your healthcare provider before testing.
What Happens During the Test
A healthcare professional will insert a needle into a vein in your arm and collect a blood sample. You may feel slight discomfort, but it usually lasts only a few seconds. The sample is then sent to a lab for analysis.
What the Results Mean
Results are reported in units per liter (IU/L). Low or undetectable levels may indicate no pregnancy or early miscarriage. Very high levels could suggest complications like ectopic pregnancy or certain cancers. Your doctor will interpret results based on your medical history and symptoms.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
hCG levels are critical in pregnancy diagnosis, monitoring fetal development, and identifying complications. Elevated levels may signal multiple pregnancies or molar pregnancy, while persistently low levels could indicate early pregnancy failure. In non-pregnant individuals, abnormal hCG can signal conditions like ovarian tumors or gestational trophoblastic disease.
Short name
hCG Level
Frequently asked questions
When might I need this test?
What are typical hCG reference ranges?
Can I take anything before the test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy