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Serum or plasma concentration of human chorionic gonadotropin (hCG)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of human chorionic gonadotropin (hCG), a hormone produced during pregnancy, in your blood or serum.

Quick summary

["Helps confirm pregnancy or detect early pregnancy loss."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
77191-5
Short code
Deprecated HE4 SerPl EIA-sCnc
Synonyms
Deprecated HE4 SerPl EIA-sCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
eia
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors order an hCG test to confirm pregnancy, especially when early symptoms like missed periods, nausea, or breast tenderness appear. It may also be used to monitor high-risk pregnancies, check for ectopic pregnancies, or evaluate fertility treatments. In some cases, it can help diagnose conditions like ovarian tumors or certain cancers.

What to Expect Before the Test

No special preparation is needed, but you may be asked to fast for 8–12 hours before the blood draw if your lab requires it. Wear comfortable clothing and plan to stay for the procedure, as it typically takes a few minutes. If you’re pregnant, inform your healthcare provider before testing.

What Happens During the Test

A healthcare professional will insert a needle into a vein in your arm and collect a blood sample. You may feel slight discomfort, but it usually lasts only a few seconds. The sample is then sent to a lab for analysis.

What the Results Mean

Results are reported in units per liter (IU/L). Low or undetectable levels may indicate no pregnancy or early miscarriage. Very high levels could suggest complications like ectopic pregnancy or certain cancers. Your doctor will interpret results based on your medical history and symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

hCG levels are critical in pregnancy diagnosis, monitoring fetal development, and identifying complications. Elevated levels may signal multiple pregnancies or molar pregnancy, while persistently low levels could indicate early pregnancy failure. In non-pregnant individuals, abnormal hCG can signal conditions like ovarian tumors or gestational trophoblastic disease.

Short name

hCG Level

Frequently asked questions

When might I need this test?
You may need an hCG test if you’re experiencing early pregnancy symptoms, have missed your period, or are undergoing fertility treatments. Doctors also use it to monitor pregnancies at high risk or after miscarriage/ectopic pregnancy diagnosis.
What are typical hCG reference ranges?
Reference ranges vary by lab and pregnancy stage. Early pregnancy hCG levels rise gradually; a single test alone cannot confirm viability. Your doctor will compare results with your symptoms and medical history.
Can I take anything before the test?
Follow your doctor’s instructions—some labs require fasting, while others do not. Avoid smoking or caffeine before the blood draw if advised by your provider.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy