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House Dust Allergen-Specific IgE Antibody, Serum — Radioallergosorbent (RAST), Qualitative

Published: August 9, 2026Updated: August 17, 2026

A blood test that looks for IgE antibodies to house dust allergens, including common dust mite proteins, to help evaluate suspected allergic sensitization.

Quick summary

["A positive result suggests an allergy-related immune response to house dust or dust mite allergens."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
21344-7
Short code
Deprecated House Dust Greer IgG RAST Ql
Synonyms
Deprecated House Dust Greer IgG RAST Ql
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
10
Ref high
40
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84484
SNOMED
302774002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This test measures allergen-specific IgE antibodies in the blood that react with house dust allergens, such as proteins from common dust mites. It is sometimes called a radioallergosorbent test, or RAST.

Why might I need this test?

Your clinician may order it when you have sneezing, congestion, wheezing, or eye symptoms that seem related to dust or dust mites. It can help identify whether these allergens trigger an immune response.

How is the test performed?

A blood sample is collected and the serum is tested in the laboratory for antibodies against house dust allergens. Unlike a skin-prick test, this test does not require the allergen to be placed under your skin.

How do I prepare for the test?

Fasting is usually not required. Tell your clinician about any allergy medicines or immune treatments you use, and follow their instructions if they advise changing or holding a medication before testing.

Reference range

Adult: 10-40 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

A positive result indicates that your immune system has produced IgE antibodies to a house dust or dust mite allergen. This supports allergic sensitization but should be interpreted with your symptoms, exposure history, and other allergy evaluation findings. A negative result does not completely rule out an allergy because some relevant allergens may not be represented in the test.

Short name

House dust-specific IgE (RAST)

Frequently asked questions

Does a positive result mean I am allergic to house dust?
It indicates sensitization to an allergen found in house dust, often a dust mite protein. Your clinician will interpret this alongside your symptoms because sensitization does not always cause symptoms.
Is this the same as a dust mite skin-prick test?
Both evaluate allergic sensitization, but this test uses a blood sample rather than placing allergens on the skin. The skin-prick test and this laboratory test are not always interchangeable.
Can I use the result to choose allergy treatment?
Your clinician may use the result with your history to guide treatment or avoidance recommendations. It should not be used by itself to select medicines, determine allergy severity, or confirm the cause of every symptom.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy