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Porcine Insulin-Specific IgE Antibody (RAST), Qualitative — Deprecated

Published: August 9, 2026Updated: August 17, 2026

A qualitative, deprecated blood test that detects IgE antibodies directed against porcine insulin, which may help evaluate a suspected immediate allergic reaction.

Quick summary

["A positive result indicates IgE sensitization to porcine insulin, but symptoms and clinical history are needed to determine whether it is causing an allergy."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
15794-1
Short code
Deprecated Insulin Porcine IgE RAST Ql
Synonyms
Deprecated Insulin Porcine IgE RAST Ql
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
10
Ref high
40
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84484
SNOMED
302774002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This is an older qualitative test, called a RAST test, that measures IgE antibodies directed against porcine insulin. A positive result shows immune sensitization, while a negative result means that detectable specific IgE was not found.

Why might I need this test?

The test may be considered when a person has an immediate reaction, such as hives, wheezing, swelling, or low blood pressure, after receiving porcine-derived insulin. It can also help evaluate suspected IgE-mediated allergy to animal-derived insulin products.

How is the test performed?

A blood-based sample is tested for porcine insulin-specific IgE using an allergen-specific immunoassay. The result is reported qualitatively as positive or negative rather than with a numeric concentration.

How do I prepare for the test?

No special preparation or fasting is generally required. Tell your clinician about the timing of any reaction, the type of insulin you received, and all symptoms that occurred.

Reference range

Adult: 10-40 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

A positive result indicates that IgE antibodies to porcine insulin are present, suggesting possible immediate hypersensitivity. This finding should be interpreted with the exposure history and symptoms because sensitization does not always mean that the substance caused a past reaction. A negative result makes IgE-mediated allergy less likely but does not completely exclude it.

Short name

Porcine insulin IgE antibody

Frequently asked questions

What does a positive porcine insulin IgE test mean?
It means that your immune system has produced detectable IgE antibodies against porcine insulin, suggesting sensitization. Your clinician will consider this together with your symptoms and exposure history.
Does this test prove that porcine insulin caused an allergic reaction?
No. A positive result shows sensitization, not necessarily the cause of a specific reaction. Clinical evaluation is needed to determine whether the result is clinically relevant.
Why is this test listed as deprecated?
This is an older testing method and is no longer routinely recommended. More modern allergen-specific IgE testing methods may be used instead when clinically appropriate.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy