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Fecal Lactoglobulin IgA, Qualitative (Deprecated)

Published: August 9, 2026Updated: August 17, 2026

A stool test for lactoglobulin IgA, an older marker of intestinal inflammation. This test is deprecated and has largely been replaced by fecal calprotectin or lactoferrin testing.

Quick summary

["This deprecated stool test can indicate intestinal inflammation, but it should not be used by itself to diagnose a specific condition."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
25456-5
Short code
Deprecated Lactoglob IgA RAST Ql
Synonyms
Deprecated Lactoglob IgA RAST Ql
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
10
Ref high
40
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84484
SNOMED
302774002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

Fecal lactoglobulin IgA is a laboratory test that examines stool for lactoglobulin IgA, a substance released during intestinal inflammation. The qualitative version reports whether the marker is detected. This test has been deprecated and is not routinely used in current clinical practice.

Why might I need this test?

This test was historically used to help evaluate unexplained intestinal symptoms, such as abdominal pain, diarrhea, or blood in the stool. It may have been ordered when inflammatory bowel disease or another source of intestinal inflammation was suspected.

How is the test performed?

A stool sample is collected and analyzed in the laboratory to determine whether lactoglobulin IgA is present. Because the test is deprecated, results may be obtained only from archived records or specialized laboratory testing.

How do I prepare for the test?

Follow the laboratory's stool-collection instructions and tell the clinician if you recently took antibiotics or other medicines that could affect intestinal inflammation. If the test is being performed as part of current evaluation, ask whether fecal calprotectin or lactoferrin would be more appropriate.

Reference range

Adult: 10-40 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Fecal Lactoglobulin IgA

Frequently asked questions

Is fecal lactoglobulin IgA still routinely used?
No. The test is deprecated and is generally replaced by fecal calprotectin or fecal lactoferrin, which are more commonly used to evaluate intestinal inflammation.
What does a positive result mean?
A positive result suggests inflammation somewhere in the digestive tract. It does not by itself confirm inflammatory bowel disease or distinguish inflammation from infection or another cause.
Does a negative result rule out inflammatory bowel disease?
No. A negative result makes some inflammatory conditions less likely but does not completely exclude them, particularly if symptoms are persistent or the test was performed during a period of reduced inflammation.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy