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Rheumatoid Factor — Latex Agglutination, Qualitative

Published: August 9, 2026Updated: August 17, 2026

A qualitative test that checks a blood sample for rheumatoid factor antibodies using latex agglutination.

Quick summary

["A positive result can support the evaluation of rheumatoid arthritis, but it must be interpreted with your symptoms and other tests."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
82602-4
Short code
Deprecated Latex (rHev b) 10 IgE RAST Ql
Synonyms
Deprecated Latex (rHev b) 10 IgE RAST Ql
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
10
Ref high
40
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84484
SNOMED
302774002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This test looks for rheumatoid factor, an antibody that can attack the body's own tissues, especially joints. It uses a latex agglutination method to provide a qualitative result.

Why might I need this test?

Rheumatoid factor testing may be ordered when joint pain, swelling, morning stiffness, or other symptoms suggest an inflammatory condition. It is often evaluated alongside other laboratory and clinical findings.

How is the test performed?

A laboratory combines the patient's specimen, commonly blood serum, with a latex reagent. If rheumatoid factor is present, visible clumping called agglutination may occur; the result is reported as positive or negative.

How do I prepare for the test?

This test usually requires no special preparation or fasting. Follow any instructions from your healthcare professional and tell the laboratory if you have recently received treatments that could affect the result.

Reference range

Adult: 10-40 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

A positive result may occur with rheumatoid arthritis, but it can also be associated with certain infections, other autoimmune conditions, or aging. A negative result does not completely exclude rheumatoid arthritis, so the result should be interpreted with symptoms, examination findings, and other tests.

Short name

Rheumatoid factor test

Frequently asked questions

Does a positive result mean I have rheumatoid arthritis?
Not necessarily. Rheumatoid factor can be positive in people without rheumatoid arthritis, and some people with the disease test negative.
Is this the same as an anti-CCP test?
No. This test detects rheumatoid factor, while an anti-CCP test detects a different antibody that is often more specific for rheumatoid arthritis. Both may be used during evaluation.
Does the qualitative result provide a measured concentration?
No. The result is generally reported as positive or negative rather than as a specific concentration. A separate quantitative test may be ordered if a measured level is needed.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy