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Extended Liver Function Test with Ammonia and AST — Qualitative

Published: August 9, 2026Updated: August 17, 2026

A legacy qualitative liver test that includes AST and ammonia. It helps evaluate liver injury and how the body handles ammonia.

Quick summary

["This test looks for signs of liver dysfunction and impaired ammonia processing."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
15808-9
Short code
Deprecated Ltx Glv Ext Ammon IgE RAST Ql
Synonyms
Deprecated Ltx Glv Ext Ammon IgE RAST Ql
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
10
Ref high
40
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84484
SNOMED
302774002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This is a legacy, extended liver-function test that includes aspartate aminotransferase (AST) and ammonia. Some laboratories may include additional liver-related measurements, and this version reports a qualitative result.

Why might I need this test?

It may be ordered to evaluate suspected liver disease, monitor liver problems, or investigate confusion, unusual fatigue, or other symptoms that could be related to the liver or the buildup of ammonia.

How is the test performed?

A laboratory specimen, usually blood, is analyzed for AST, ammonia, and any other components included by the testing laboratory. Blood used for ammonia testing may need special handling and prompt processing.

How do I prepare for the test?

Follow the laboratory's instructions and tell the healthcare provider about medicines, supplements, alcohol use, and recent illness. Avoid eating or drinking only if you are specifically told to fast, and do not stop prescribed medicines unless instructed.

Reference range

Adult: 10-40 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

An abnormal AST result may occur with liver-cell injury, alcohol-related liver disease, medication effects, muscle injury, or other conditions. An abnormal ammonia result can reflect impaired liver function, reduced blood flow to the liver, certain medicines, or problems involving the kidneys. The overall pattern must be interpreted by a healthcare professional because individual results do not establish a diagnosis.

Short name

Extended liver function test

Frequently asked questions

What does AST measure?
AST is an enzyme found in the liver and several other tissues. An elevated result can indicate tissue injury, including liver injury, but it is not specific to the liver.
Why is ammonia included?
Ammonia is a breakdown product that the liver helps process. Elevated levels may contribute to confusion or other neurologic symptoms when the liver is not functioning normally.
Why was this test labeled deprecated?
It is an older test version that many laboratories have replaced with updated panels or standardized quantitative methods. Ask the ordering clinician whether a newer liver test would be more appropriate.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy