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C-reactive protein (CRP) concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of C-reactive protein, a substance produced by the liver in response to inflammation in your body.

Quick summary

["CRP helps identify inflammation, often used to monitor conditions like infections, autoimmune diseases, or after surgery."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
60423-1
Short code
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Synonyms
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Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
organism-specific-culture
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Doctors may order CRP tests to check for signs of inflammation, monitor chronic conditions like arthritis or heart disease, or evaluate responses to treatments. It can also help diagnose infections or assess risks after procedures.

What to Expect During the Test

A blood sample is taken from a vein, usually in your arm. You may feel a small pinch, but it’s quick. No special preparation is needed unless instructed otherwise.

Common Uses and Conditions

CRP is commonly used to screen for conditions like sepsis, rheumatoid arthritis, or cardiovascular risks. It may also guide decisions about starting or stopping certain medications.

What the Results Might Mean

Higher-than-normal CRP levels often indicate inflammation, but they can also be influenced by factors like stress, recent illness, or certain medications. Always discuss results with your healthcare provider.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

CRP

Frequently asked questions

CRP is a marker for systemic inflammation and is widely used in clinical practice to assess disease activity, monitor treatment responses, and guide preventive care, particularly in cardiovascular and autoimmune diseases.
How often should I get this test?
The frequency depends on your health condition. For example, people with chronic diseases like rheumatoid arthritis may get CRP tests every few months, while others may only need it once.
Can diet or exercise affect CRP levels?
Yes, lifestyle factors like diet, exercise, and weight can influence CRP levels. Eating a heart-healthy diet, staying active, and managing stress may help lower inflammation.
An elevated CRP level may signal inflammation that needs further investigation. Your doctor will review your symptoms, medical history, and other test results to determine the next steps.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy