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Mitochondrial Antibody Profile (Screening) – Serum

Published: August 9, 2026Updated: August 16, 2026

This test checks for antibodies against mitochondrial proteins, which may be linked to certain autoimmune conditions affecting the liver, kidneys, or other organs.

Quick summary

["This screening helps identify potential autoimmune disorders that could affect your organs over time."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
27215-3
Short code
Deprecated Mitochondria M2 IgG Ser-aCnc
Synonyms
Deprecated Mitochondria M2 IgG Ser-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like fatigue, joint pain, or unexplained liver/kidney issues, or if you have a family history of autoimmune diseases like autoimmune hepatitis or chronic kidney disease.

What to Expect Before the Test

No special preparation is needed. You’ll provide a blood sample drawn from a vein in your arm. It’s quick and usually done in a doctor’s office or lab.

What the Results Mean

Positive results suggest a higher likelihood of mitochondrial-related autoimmune conditions, but further testing (like confirmatory assays) and clinical evaluation are needed to diagnose specific disorders.

Common Conditions Linked to Positive Results

Positive results may indicate autoimmune hepatitis, chronic active hepatitis, or other rare autoimmune syndromes affecting the liver, kidneys, or nerves.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test is primarily a screening tool. Elevated antibody levels don’t confirm a diagnosis alone; they guide further testing and medical evaluation to determine the exact cause of symptoms.

Short name

Mitochondrial Antibody Screen

Frequently asked questions

How long does it take to get results?
Results are typically available within 1–3 business days, depending on lab processing times.
What does a positive result mean for my health?
A positive result may mean you’re at higher risk for certain autoimmune conditions, but it doesn’t mean you have one. Your doctor will discuss next steps, such as additional tests or monitoring.
Can I eat or drink before this test?
No special diet is required, but avoid heavy meals or alcohol before your blood draw to ensure accuracy.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy