Total Protein (Serum or Plasma)
This test measures the total amount of protein in your blood, which includes albumin and other proteins like globulins.
["Your blood protein levels help assess overall health and detect potential issues like malnutrition or kidney problems."]
Key facts at a glance
- LOINC
- 23317-1
- Short code
- Deprecated NSDV Ab Titr Ser
- Synonyms
- Deprecated NSDV Ab Titr Ser
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why Is This Test Done?
Doctors may order a total protein test to check for conditions like malnutrition, kidney disease, liver problems, or certain types of infections. It can also help diagnose autoimmune disorders or monitor long-term health in people with chronic illnesses.
What Does the Result Mean?
Higher-than-normal levels might suggest conditions like multiple myeloma, severe dehydration, or certain inflammatory diseases. Lower-than-normal levels could indicate malnutrition, kidney disease, or liver problems. However, results alone don’t diagnose a condition—your doctor will consider your full medical picture.
Sample Preparation and Collection
This test is typically done on a blood sample collected from a vein in your arm. You may be asked to fast before the test, but this isn’t always required. Avoid strenuous activity or certain medications for a few days before your appointment if instructed.
What to Expect During the Test
The process is quick and usually painless. A healthcare professional will insert a small needle into your vein to draw blood. You may feel a slight pinch, but the procedure takes only a few minutes. You can usually return to normal activities immediately afterward.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Total Protein
Frequently asked questions
What causes low total protein levels?
What causes high total protein levels?
How often should I get this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy