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Oyster-Specific IgG Antibody, Qualitative (RAST) — Deprecated

Published: August 9, 2026Updated: August 17, 2026

A qualitative blood test that detects antibodies directed against oyster proteins. This deprecated test is not considered a reliable stand-alone test for oyster allergy.

Quick summary

["A positive result shows an immune response to oyster proteins but does not by itself confirm an oyster allergy."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
21438-7
Short code
Deprecated Oyster IgG RAST Ql
Synonyms
Deprecated Oyster IgG RAST Ql
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
10
Ref high
40
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84484
SNOMED
302774002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This test looks for oyster-specific IgG antibodies in a blood sample using a qualitative RAST-type laboratory assay. The result is generally reported as positive or negative.

Why might I need this test?

It may have been ordered to evaluate an immune response after eating oysters or when investigating a suspected food reaction. The test is now deprecated and should not be used alone to diagnose or rule out food allergy.

How is the test performed?

A blood sample is analyzed in the laboratory for antibodies that bind to oyster proteins. The laboratory reports whether oyster-specific IgG was detected.

How do I prepare for the test?

No special preparation is usually specified for this qualitative antibody test. Follow any instructions from your clinician or laboratory, and tell them if you have recently eaten oysters or had a reaction.

Reference range

Adult: 10-40 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

A positive result may indicate prior exposure or an immune response to oyster proteins, but it does not necessarily mean you have a clinical oyster allergy. A negative result does not exclude allergy or a reaction. Because this test is deprecated, results should be interpreted alongside symptoms, medical history, and any more appropriate allergy testing.

Short name

Oyster-specific IgG

Frequently asked questions

Does a positive result mean I am allergic to oysters?
No. Detectable oyster-specific IgG can occur after exposure and is not equivalent to a clinically significant allergy. Your clinician should interpret the result with your symptoms and medical history.
Can a negative result rule out oyster allergy?
No. A negative result cannot exclude allergy, especially if symptoms occurred shortly after eating oysters. Skin-prick or other clinician-directed testing may be more appropriate when allergy is suspected.
Why is this test listed as deprecated?
Oyster-specific IgG testing is no longer considered a dependable stand-alone method for diagnosing food allergy. Newer, more clinically relevant evaluation approaches are generally preferred.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy