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Rheumatoid Factor IgG, Qualitative (PAN IgG RAST; Deprecated)

Published: August 9, 2026Updated: August 17, 2026

An older qualitative test that detects IgG rheumatoid factor in a patient sample. Positive results can support evaluation for rheumatoid arthritis but require clinical correlation.

Quick summary

["A positive result suggests IgG rheumatoid factor is present, but it does not by itself diagnose rheumatoid arthritis."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
33302-1
Short code
Deprecated PAN IgG RAST Ql
Synonyms
Deprecated PAN IgG RAST Ql
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
10
Ref high
40
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84484
SNOMED
302774002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This is an older qualitative laboratory test for IgG rheumatoid factor, an antibody that can react against the body's own IgG. It is also known by the historical term PAN IgG RAST and has been deprecated, so it may not be available for new orders.

Why might I need this test?

Rheumatoid factor testing may be considered when symptoms suggest rheumatoid arthritis, such as persistent joint swelling, pain, or morning stiffness. It may also be used as part of an evaluation for other autoimmune conditions.

How is the test performed?

A patient sample is analyzed with a qualitative method to determine whether IgG rheumatoid factor is present. The laboratory may report the result as positive or negative, although current testing often uses a quantitative assay.

How do I prepare for the test?

No special preparation is usually required for this type of antibody test. Follow your clinician's or laboratory's instructions, and ask whether fasting is needed if the test is being performed with other laboratory studies.

Reference range

Adult: 10-40 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

A positive result means IgG rheumatoid factor was detected. This can occur with rheumatoid arthritis, but it may also be present with other autoimmune diseases, certain infections, some medications, or in some healthy people, so the result must be interpreted with symptoms and other findings. A negative result does not completely exclude rheumatoid arthritis.

Short name

IgG Rheumatoid Factor (Qualitative)

Frequently asked questions

Does a positive result mean I have rheumatoid arthritis?
No. IgG rheumatoid factor can be present in conditions other than rheumatoid arthritis and sometimes in healthy people, so a clinician must interpret it alongside your symptoms, examination, and other tests.
What if the result is negative?
A negative result does not rule out rheumatoid arthritis, particularly early in the disease or when only some types of rheumatoid factor are present. Your clinician may consider repeat testing or other investigations if symptoms persist.
Why is this test marked as deprecated?
This is an older qualitative form of rheumatoid factor testing and is no longer the usual choice for new orders. A current laboratory can often provide an equivalent or quantitative rheumatoid factor test.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy