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Perennial Aeroallergen-Specific IgG Radioallergosorbent Test (PEAR IgG RAST), Qualitative (Deprecated)

Published: August 9, 2026Updated: August 17, 2026

A legacy qualitative blood test for IgG antibodies to perennial allergens. It is not the same as standard IgE-based allergy testing.

Quick summary

["This deprecated IgG RAST test is not standard IgE allergy testing, so its result should be interpreted with your clinician."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
21448-6
Short code
Deprecated Pear IgG RAST Ql
Synonyms
Deprecated Pear IgG RAST Ql
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
10
Ref high
40
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84484
SNOMED
302774002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

PEAR stands for perennial aeroallergen. This qualitative RAST test looks for allergen-specific IgG antibodies associated with common perennial allergens, such as dust mites, animal dander, and molds.

Why might I need this test?

This legacy test may have been used to assess prior exposure or sensitization to perennial allergens. It has been deprecated and should not be confused with standard allergy testing that measures allergen-specific IgE.

How is the test performed?

A blood sample is collected, separated into serum, and exposed to selected allergen components. The laboratory uses the RAST detection method to determine whether matching allergen-specific antibodies are present.

How do I prepare for the test?

No special preparation is generally required for a blood draw. Because this is a deprecated test, contact the laboratory before the appointment to confirm that it is still available and which allergens are included.

Reference range

Adult: 10-40 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

PEAR IgG RAST

Frequently asked questions

Is this the same as a standard RAST allergy test?
No. Standard RAST testing usually measures allergen-specific IgE, while this deprecated label refers to an IgG assay. Confirm the exact analyte with the laboratory or ordering clinician.
Does a positive result mean I am allergic?
Not necessarily. Allergen-specific IgG can indicate exposure or sensitization and does not alone prove that symptoms are caused by an IgE-mediated allergy.
What should I do with the result?
Review it with your clinician, who can interpret it alongside your symptoms, exposure history, and any more current allergy testing.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy