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Serum Free Fructosamine

Published: August 9, 2026Updated: August 16, 2026

This test measures the average blood sugar levels over the past two to three weeks by tracking a protein called hemoglobin that has been exposed to sugar. It helps assess long-term glucose control, particularly useful for people with diabetes.

Quick summary

["A useful tool to check how well your blood sugar has been managed over time."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
14120-0
Short code
Deprecated PSA Free Fr SerPl
Synonyms
Deprecated PSA Free Fr SerPl
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0
Ref high
4
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84153
SNOMED
39392002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Doctors may order this test to monitor long-term blood sugar control in people with diabetes. Unlike hemoglobin A1c, which reflects average glucose levels over roughly three months, fructosamine gives a slightly shorter but still meaningful snapshot of how your body has handled sugar in recent weeks.

What Does the Result Mean?

Results are not provided as a specific numeric range, but they help healthcare providers determine if your blood sugar levels have been consistently within target ranges. Abnormally high or low levels may indicate poor glucose management or other health concerns.

How Is the Test Performed?

A blood sample is taken from a vein, usually in your arm. The sample is then processed to measure free fructosamine levels in your serum.

What Are Common Causes of Abnormal Results?

Elevated levels may suggest poor diabetes management, stress, infection, or certain medications. Low levels could indicate advanced diabetes complications, severe illness, or other metabolic issues.

Reference range

Normal: <4.0 ng/mLN/A

Specimen: serum

No special preparation required. For PSA, avoid sexual activity for 24-48 hours before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: This test is particularly valuable for patients with diabetes who may not have stable glucose levels or those who cannot have an A1c test (e.g., due to hemolytic anemia or other conditions). It provides an alternative or complementary measure of glycemic control, especially in acute or unstable health states.

Short name

Free Fructosamine Level

Frequently asked questions

Why might my doctor request this test instead of an A1c?
If your doctor prefers a test that reflects more recent glucose trends (within weeks rather than months) or if you have conditions that might interfere with A1c results (like certain blood disorders), they may choose this test. It also helps track changes in glucose control more quickly.
How often should I get this test?
Your doctor will determine the frequency based on your diabetes management plan. Typically, it may be done alongside other tests like A1c or blood sugar monitoring to provide a full picture of your health.
Can lifestyle changes affect this test result?
Yes, diet, exercise, and medications (like insulin or oral diabetes drugs) can impact blood sugar levels and thus your fructosamine result. Consistently following your treatment plan can help stabilize these levels.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy