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Urine Protein Electrophoresis, Qualitative

Published: August 9, 2026Updated: August 17, 2026

A urine test that separates proteins into groups to identify abnormal protein patterns associated with kidney or plasma-cell disorders.

Quick summary

["This test helps identify unusual urine protein patterns that may indicate kidney disease or increased monoclonal light chains."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
15973-1
Short code
Deprecated Rabbit Urine Prot IgE RAST Ql
Synonyms
Deprecated Rabbit Urine Prot IgE RAST Ql
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
10
Ref high
40
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84484
SNOMED
302774002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

Urine protein electrophoresis is a laboratory method that separates proteins in urine into different groups. A qualitative result reports which protein fractions are present rather than providing exact measurements.

Why might I need this test?

This test may be used to evaluate unexplained protein in the urine or help identify the source of a protein pattern. It can also support evaluation for conditions affecting antibody-producing plasma cells, including multiple myeloma.

How is the test performed?

A urine sample is analyzed in the laboratory using electrophoresis. The resulting protein bands or fractions are reviewed to determine whether the pattern is normal or abnormal.

How do I prepare for the test?

Urine protein electrophoresis generally uses a routine or first-morning urine sample unless your clinician requests a timed collection. Follow the laboratory's collection instructions, and tell the clinician if you are taking medicines or recently had an infection.

Reference range

Adult: 10-40 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

An abnormal result may indicate increased urinary albumin, light chains, or other proteins associated with kidney dysfunction. An unusual monoclonal protein pattern can suggest a plasma-cell disorder but does not establish that diagnosis by itself and may require blood, urine, or imaging tests for confirmation.

Short name

Urine protein electrophoresis

Frequently asked questions

Does this test diagnose multiple myeloma?
No. It can reveal a protein pattern that raises concern for a plasma-cell disorder, but diagnosis requires additional clinical and laboratory evidence.
Is a urine protein electrophoresis result the same as a routine urinalysis?
No. Routine urinalysis screens for protein and other substances, while electrophoresis separates urine proteins into fractions to provide more detail about their pattern.
Do I need to collect urine for a specific number of hours?
Usually, a routine or first-morning sample is sufficient. If a timed collection is requested, follow the specific instructions provided by the laboratory or clinician.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy