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Allergen-Specific IgE Antibody (RAST), Qualitative

Published: August 9, 2026Updated: August 17, 2026

A qualitative blood test for allergen-specific IgE that helps identify sensitization to selected triggers such as pollen, foods, dust mites, or animal dander.

Quick summary

["This test looks for IgE antibodies to specific allergens, but results must be interpreted alongside your symptoms and medical history."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
33312-0
Short code
Deprecated R nigricans IgG RAST Ql
Synonyms
Deprecated R nigricans IgG RAST Ql
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
10
Ref high
40
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84484
SNOMED
302774002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This is a blood test, commonly called RAST, that detects allergen-specific IgE antibodies. It may be ordered for one allergen or as a panel. The RAST format may be listed as deprecated in some laboratory catalogs, and a current allergen-specific IgE assay may be used instead.

Why might I need this test?

Your clinician may order this test to evaluate possible allergies to foods, pollen, dust mites, animal dander, insect venom, or other triggers. It can help identify which allergens deserve further evaluation or avoidance counseling.

How is the test performed?

A blood sample is collected from a vein and tested in the laboratory for IgE directed against selected allergens. Some laboratories use a panel, while others test only the allergens requested by your clinician.

How do I prepare for the test?

Fasting is usually not required. Antihistamines and some other allergy medicines may affect results, so tell your clinician about all medications and supplements before testing. Do not stop prescribed medicines unless your clinician instructs you to do so.

Reference range

Adult: 10-40 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Allergen-Specific IgE (RAST)

Frequently asked questions

What does a positive RAST result mean?
It means IgE antibodies to the tested allergen were detected. Your clinician will interpret this finding along with your exposure history and symptoms to determine whether it is clinically meaningful.
Does a positive result confirm an allergy?
Not necessarily. A positive result shows sensitization and may support an allergy diagnosis when it matches your symptoms, but some people have positive results without symptoms.
Should I stop taking allergy medicine before the test?
Ask your clinician first, because antihistamines can sometimes reduce detectable IgE. Do not discontinue prescribed medication without medical guidance.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy