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Staphylococcus aureus Enterotoxin D, Stool — Qualitative

Published: August 9, 2026Updated: August 17, 2026

A qualitative stool test that detects the toxin produced by Staphylococcus aureus, sometimes used when staphylococcal food poisoning is suspected.

Quick summary

["A positive result indicates that S. aureus enterotoxin D was detected in the stool."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
25827-7
Short code
Deprecated S aureus Etx D IgE RAST Ql
Synonyms
Deprecated S aureus Etx D IgE RAST Ql
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
10
Ref high
40
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84484
SNOMED
302774002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This test looks for Staphylococcus aureus enterotoxin D in a stool sample. Staphylococcal food poisoning can cause sudden vomiting, abdominal cramps, and diarrhea.

Why might I need this test?

It may be considered in selected cases of suspected food poisoning, especially when symptoms begin soon after eating a contaminated food. This is a specialized or historical test and may not be routinely offered.

How is the test performed?

A stool sample is collected and tested for the presence of enterotoxin D using a laboratory-validated method. A qualitative result reports whether the toxin was detected or was not detected.

How do I prepare for the test?

Follow the laboratory's collection instructions. Usually, you will be asked to provide a fresh stool sample in the supplied container; antibiotics or other medicines should be discussed with your clinician before collection if they could affect the results.

Reference range

Adult: 10-40 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

A positive result means that Staphylococcus aureus enterotoxin D was detected in the stool and can support a diagnosis of toxin-mediated staphylococcal food poisoning. A negative result does not completely exclude staphylococcal poisoning because testing is not always sensitive and other causes of similar symptoms are more common. Results should be interpreted with the timing of symptoms, possible food exposure, and other clinical findings.

Short name

S. aureus enterotoxin D stool test

Frequently asked questions

Does a positive result mean I have a Staphylococcus aureus infection?
Not necessarily. It indicates that the bacterial toxin was detected and is most relevant to food poisoning caused by contaminated food rather than a routine skin or bloodstream infection.
What symptoms can staphylococcal food poisoning cause?
Common symptoms include sudden nausea, forceful vomiting, abdominal cramps, and diarrhea. Symptoms often begin within a few hours after eating contaminated food.
Why might this test be unavailable?
This is a specialized and potentially deprecated laboratory test, so it may not be routinely offered. Your clinician can determine whether an alternative stool or food testing strategy is appropriate.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy