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Staphylococcus aureus Toxic Shock Syndrome Toxin-1 IgE Antibody, Qualitative (Deprecated)

Published: August 9, 2026Updated: August 17, 2026

A qualitative test that detects IgE antibodies directed against Staphylococcus aureus toxic shock syndrome toxin-1 (TSST-1).

Quick summary

["A positive result suggests sensitization to TSST-1 but does not by itself confirm an allergy or toxic shock syndrome."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
51863-9
Short code
Deprecated S aureus TSST-1 IgE RAST Ql
Synonyms
Deprecated S aureus TSST-1 IgE RAST Ql
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
10
Ref high
40
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84484
SNOMED
302774002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This laboratory test looks for IgE antibodies against toxin-1 produced by Staphylococcus aureus bacteria. The result is reported qualitatively, usually as detectable or not detectable.

Why might I need this test?

It may be used in specialized evaluations of suspected IgE-mediated sensitization to the toxin, particularly when symptoms repeatedly follow certain exposures. It is not a routine test for a Staphylococcus aureus infection or for diagnosing toxic shock syndrome.

How is the test performed?

The laboratory uses an antibody-detection method to determine whether TSST-1-specific IgE is present in the submitted specimen. The exact testing method and specimen requirements depend on the laboratory.

How do I prepare for the test?

Special preparation is usually not required. Tell the healthcare provider about allergic reactions, medication use, and any recent treatment with biologic drugs or immunoglobulin, because these may affect antibody-test results.

Reference range

Adult: 10-40 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

A detectable result suggests that the immune system has produced IgE directed against TSST-1, which can be consistent with sensitization. It does not prove that exposure will cause symptoms and must be interpreted with the clinical history. This result alone cannot establish an active Staphylococcus aureus infection or toxic shock syndrome.

Short name

Staph aureus TSST-1 IgE antibody

Frequently asked questions

Does a positive result mean I have a Staphylococcus aureus infection?
No. This test detects antibodies related to sensitization; it does not show that an infection is currently present.
Does a positive result confirm toxic shock syndrome?
No. Toxic shock syndrome is diagnosed from symptoms and other clinical findings, not from this antibody test alone.
Why is this test marked as deprecated?
The test is no longer routinely available or is being replaced by another laboratory method. Ask the ordering clinician whether an alternative test is appropriate.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy