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Shagbark Hickory-Specific IgE (RAST), Qualitative

Published: August 9, 2026Updated: August 17, 2026

A qualitative blood test that detects IgE antibodies to shagbark hickory, helping assess sensitization to this tree nut.

Quick summary

["A positive result indicates an immune response to shagbark hickory but does not by itself confirm a clinical allergy."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
21329-8
Short code
Deprecated Shagbark Hickory IgE RAST Ql
Synonyms
Deprecated Shagbark Hickory IgE RAST Ql
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
10
Ref high
40
Critical range
— – 10000 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84484
SNOMED
302774002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This test looks for allergen-specific IgE antibodies directed against shagbark hickory, a tree nut. It is sometimes called a RAST test, although current laboratory methods may use other immunoassay technology.

Why might I need this test?

It may be ordered if you have eaten shagbark hickory or another tree nut and developed symptoms such as hives, swelling, wheezing, vomiting, or abdominal pain. Your clinician will interpret the result along with your exposure history and symptoms.

How is the test performed?

A laboratory analyzes a blood sample for IgE antibodies to shagbark hickory. This qualitative result is generally reported as positive or negative, although some laboratories may also provide a measurement level.

How do I prepare for the test?

No fasting or special preparation is usually required. Do not intentionally eat shagbark hickory before testing, and follow any additional instructions provided by the ordering clinician or laboratory.

Reference range

Adult: 10-40 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

A positive result indicates sensitization to shagbark hickory, meaning the immune system has produced IgE antibodies to it. This may represent a true tree-nut allergy, but cross-reactivity with related allergens is also possible. A negative result reduces the likelihood of IgE-mediated allergy but does not completely exclude it.

Short name

Shagbark hickory IgE

Frequently asked questions

Does a positive result mean I will have an allergic reaction?
Not necessarily. It shows immune sensitization, but symptoms and the circumstances of exposure must be considered before diagnosing a clinical allergy.
Can I eat shagbark hickory if the result is positive?
Avoid it until you have discussed the result with your clinician or allergist. A positive result may lead to advice to avoid the nut and other closely related tree nuts.
Why was this test sometimes labeled deprecated?
Some laboratory databases use “deprecated” for older test names or assay methods. The allergen-specific IgE concept remains clinically relevant, although the laboratory's current testing method should be confirmed.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy