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Silver Birch-Specific IgG4 Antibody — Radioallergosorbent Test (RAST), Qualitative (Deprecated)

Published: August 9, 2026Updated: August 17, 2026

A qualitative blood test for IgG4 antibodies directed against silver birch allergen. This legacy RAST test is deprecated and is not a standard test for diagnosing allergy.

Quick summary

["This deprecated test looks for silver birch–specific IgG4 antibodies, but a result should not by itself establish an allergy diagnosis."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
26410-1
Short code
Deprecated Silver Birch IgG4 RAST Ql
Synonyms
Deprecated Silver Birch IgG4 RAST Ql
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
10
Ref high
40
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84484
SNOMED
302774002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This test looks for IgG4 antibodies that react with silver birch allergen using a radioallergosorbent test, or RAST. It is a qualitative test, meaning it reports whether the antibodies were detected rather than providing a measured concentration.

Why might I need this test?

This test may have been ordered as part of an evaluation of a suspected allergy to silver birch pollen or related exposure. It is now considered deprecated, so newer allergy testing and clinical assessment are generally preferred.

How is the test performed?

A laboratory sample is exposed to silver birch allergen in a RAST procedure that detects allergen-specific IgG4. The result is reported as detected or not detected, or with a qualitative interpretation such as negative, equivocal, or positive.

How do I prepare for the test?

No special preparation is usually required for this type of blood test. If the test is still being offered, follow the laboratory's collection instructions and tell the clinician about any allergy testing or immunotherapy you have received.

Reference range

Adult: 10-40 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Silver Birch IgG4 RAST

Frequently asked questions

Does a positive result mean I am allergic to silver birch?
Not necessarily. Silver birch–specific IgG4 can reflect exposure or tolerance and does not by itself diagnose an IgE-mediated allergy.
Why is this test listed as deprecated?
It is a legacy assay and is not generally part of current allergy evaluation. Modern testing is based mainly on allergen-specific IgE and the patient's clinical history.
Should I stop allergy immunotherapy because of this result?
Do not change allergy treatment based on this test alone. Discuss the result with your clinician or allergist, who can assess your symptoms and treatment history.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy