Skip to content

Antibody to Streptococcus pneumoniae (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of antibodies your body produces in response to the bacteria *Streptococcus pneumoniae*, which can cause serious infections like pneumonia, meningitis, or bloodstream infections.

Quick summary

["Helps identify past or current infection risk from pneumococcal bacteria."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
24021-8
Short code
Deprecated S pneum12 Ab Ser-mCnc
Synonyms
Deprecated S pneum12 Ab Ser-mCnc
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test detects specific antibodies (immunoglobulins) your immune system creates to fight *Streptococcus pneumoniae*. These antibodies are part of your body’s defense against the bacteria. The result indicates whether your immune system has encountered this bacteria before or if it’s actively responding to an infection.

Why It’s Ordered

Doctors may order this test if you have symptoms of pneumonia, ear infections, sinusitis, or other respiratory infections, especially if you’re at higher risk (e.g., young children, elderly adults, or those with weakened immune systems). It can also be used to assess exposure in certain high-risk settings (e.g., daycare centers, nursing homes).

Sample Collection and Preparation

A blood sample is taken from a vein in your arm. The blood is processed to separate serum (liquid part of blood without clots), where the antibodies are measured. This test does not require fasting.

Test Results Interpretation

Results are qualitative (positive/negative) and indicate whether detectable antibodies were found. A positive result suggests past exposure or immune response to *Streptococcus pneumoniae*, but it does not confirm an active infection. Consult your healthcare provider for clinical correlation.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Strep Pneumonia Antibody

Frequently asked questions

This test helps diagnose or monitor conditions related to pneumococcal bacteria, such as pneumonia, meningitis, or sepsis. It can also guide vaccination decisions for high-risk individuals, as immunity from antibodies may wane over time.
A positive result means your body has recognized and produced antibodies against *Streptococcus pneumoniae*, which may indicate past infection or vaccination. However, it does not replace other diagnostic tests like imaging or cultures for active infections.
How long does it take to get results?
Results are typically available within 1 to 3 business days, depending on lab processing times. Your healthcare provider will discuss the meaning of your specific result with you.
Can this test be used to diagnose pneumonia?
No, this test alone cannot diagnose pneumonia. It measures antibodies, which indicate past exposure or immune response, but doctors use clinical symptoms, imaging, and cultures to diagnose active infections.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy