Alpha-1 Antitrypsin (Serum) Mass Concentration

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like chronic cough, shortness of breath, or liver problems, or if you have a family history of lung diseases like emphysema or chronic obstructive pulmonary disease (COPD). It may also be checked before surgeries or treatments that could affect lung function.

What to Expect Before the Test

You’ll typically have a small needle inserted into your arm to draw blood. It usually takes a few minutes, and you may feel a slight pinch. No special preparation is usually needed, but check with your provider if you’re on blood thinners or have a history of bleeding disorders.

What the Results Mean

Lower than normal levels may suggest genetic conditions (like Alpha-1 Antitrypsin Deficiency), liver disease, or certain infections. Higher levels might be seen in conditions like cirrhosis or acute hepatitis. Your provider will discuss results in the context of your health history.

Common Conditions Monitored or Diagnosed

This test helps diagnose or monitor Alpha-1 Antitrypsin Deficiency, which can lead to lung diseases like emphysema or chronic bronchitis, as well as liver diseases like cirrhosis. It’s also used to assess liver function and guide treatment decisions.