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IgG Antibody to Streptococcus pneumoniae (Serum)

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of antibodies in your blood that target the bacteria *Streptococcus pneumoniae*, which can cause serious infections like pneumonia.

Quick summary

["It helps assess your immune response to pneumococcal infection or vaccination."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
22543-3
Short code
Deprecated S pneum14 IgG Ser-aCnc
Synonyms
Deprecated S pneum14 IgG Ser-aCnc
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have a history of pneumococcal infections, are at high risk for pneumonia (e.g., due to age, chronic illness, or weakened immune system), or if you’ve received pneumococcal vaccination to monitor your immune response.

What to Expect Before the Test

No special preparation is needed. You’ll have a small needle inserted into your arm to draw blood. The process usually takes a few minutes, and you may feel a brief pinch. If you’re nervous, let your provider know—some people use numbing cream or distractions.

What the Results Mean

Higher-than-normal levels may indicate your body is producing antibodies in response to infection or vaccination. Lower-than-normal levels could suggest an impaired immune response, especially if you’ve had recent exposure to pneumococcal bacteria.

Common Reasons for Testing

This test is often used in high-risk patients (e.g., children with sickle cell disease, elderly adults, or those with HIV) to track pneumococcal immunity or diagnose suspected infections.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

While not a direct diagnostic test for pneumococcal infection, elevated IgG levels can support a diagnosis if combined with clinical symptoms (e.g., fever, cough, lung imaging). It’s also used in research or vaccine studies to evaluate immune response over time.

Short name

Anti-pneumococcal IgG

Frequently asked questions

How long does it take to get results?
Results are typically available within 1–3 business days, depending on your lab’s processing time. Your provider will discuss them with you during your follow-up visit.
What if my results are abnormal?
If your IgG levels are low, your provider may recommend further testing (e.g., blood cultures, imaging) or additional vaccines to boost immunity. If high, it may indicate past exposure or vaccination success—your provider will guide next steps based on your symptoms and history.
Can I fast before this test?
No fasting is required for this blood test. However, always follow your provider’s instructions, as some tests may have specific guidelines for hydration or timing.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy