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Antibody to Streptococcus pneumoniae (Serum) – Qualitative

Published: August 9, 2026Updated: August 16, 2026

This test checks for antibodies your immune system produces in response to *Streptococcus pneumoniae*, a common bacterial cause of pneumonia, ear infections, and other illnesses.

Quick summary

["Helps identify if your body has been exposed to *Streptococcus pneumoniae* bacteria."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
17622-2
Short code
Deprecated S pneum18 Ab sp1 Ser-aCnc
Synonyms
Deprecated S pneum18 Ab sp1 Ser-aCnc
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your doctor may recommend this test if you have symptoms of infection (e.g., fever, cough, confusion) or if you’re at higher risk for complications from *Streptococcus pneumoniae*, such as children under 5, older adults, or those with weakened immune systems. It may also be used in screening for certain conditions like meningitis or sepsis.

What to Expect Before the Test

No special preparation is needed. You’ll provide a blood sample via a simple venipuncture (blood draw). The test is typically done in a lab setting and results are qualitative (yes/no) rather than quantitative.

What the Results Mean

A positive result means your body has detected antibodies to *Streptococcus pneumoniae*, suggesting past exposure. A negative result indicates no detectable antibodies at the time of testing. Results alone don’t confirm active infection—your doctor will consider symptoms, medical history, and other tests.

Common Causes of False Results

False positives or negatives can occur due to recent vaccination, prior infection, or lab errors. If results are unclear, your doctor may repeat the test or order additional tests (e.g., blood cultures) to diagnose active infection.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Strep pneumoniae Antibody Screen

Frequently asked questions

What does a positive result mean?
A positive result means your immune system has likely encountered *Streptococcus pneumoniae* before, but it doesn’t confirm an active infection. Your doctor will use these results alongside other factors (like symptoms or lab findings) to guide care.
Can I get this test if I’ve been vaccinated against pneumonia?
Yes, but vaccination may affect results. If you’ve received a *Streptococcus pneumoniae* vaccine (e.g., Pneumococcal conjugate or polysaccharide vaccine), your antibody levels may be higher, potentially giving a false-positive result. Discuss this with your doctor if you’re unsure.
How soon will I get my results?
Results are typically available within 1–3 business days, depending on lab processing. Your doctor will contact you directly with the outcome and next steps.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy