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Immunoglobulin G (IgG) in Serum, Mass Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of Immunoglobulin G (IgG), a type of antibody found in your blood. IgG helps protect your body from infections and is important for long-term immunity.

Quick summary

["IgG antibodies play a key role in defending your immune system against diseases."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
32847-6
Short code
Deprecated S pneum18 IgG Ser-mCnc
Synonyms
Deprecated S pneum18 IgG Ser-mCnc
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Immunoglobulin G (IgG)?

IgG is the most common type of antibody in your blood. It’s produced by your immune system to fight off infections and helps your body remember past illnesses, providing long-term protection. These antibodies are crucial for defending against bacteria and viruses that enter your body through cuts, infections, or other entry points.

Why Might You Need This Test?

Your doctor may order an IgG test to check for low or high levels, which can indicate conditions like immune deficiencies, chronic infections, or certain autoimmune diseases. It’s also used in monitoring treatment responses for conditions like HIV, hepatitis, or certain cancers.

When Is an IgG Test Performed?

This test is often done as part of a general health check, to diagnose or monitor conditions affecting your immune system, or to evaluate symptoms like frequent infections, fatigue, or unexplained illnesses. It may also be used during pregnancy to assess maternal-fetal immunity.

What Does the Test Involve?

A blood sample is taken from a vein in your arm. The sample is sent to a lab, where it is analyzed to measure the amount of IgG antibodies present. The results help determine if your immune system is functioning normally or if there may be an underlying issue.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

IgG Level

Frequently asked questions

What Are the Possible Causes of Abnormal IgG Levels?
Abnormal IgG levels can result from immune system disorders (e.g., immunodeficiency or autoimmune diseases), chronic infections, certain medications, or genetic factors. If your IgG is low, it may mean your body struggles to fight infections effectively. If it’s high, it could signal an overactive immune response or long-term illness.
How Long Does It Take to Get Results?
Results from an IgG test are typically available within 1 to 3 business days, depending on your lab’s processing time. Your doctor will discuss the results with you during your follow-up visit.
Can IgG Levels Change Over Time?
Yes, IgG levels can fluctuate due to factors like infections, vaccinations, medications, or underlying health conditions. Regular monitoring may be needed if you have a chronic illness or an immune-related disorder.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy