COVID-19 IgG Antibody to SARS-CoV-2 (Serum) – Mass Concentration
This test measures the presence of IgG antibodies in your serum that your immune system produces in response to exposure to the virus that causes COVID-19. IgG antibodies help your body fight off infections and provide long-term immunity.
["This test helps determine if you’ve had prior exposure to COVID-19 and may have developed immunity."]
Key facts at a glance
- LOINC
- 27406-8
- Short code
- Deprecated S pneum19f IgG Ser-mCnc
- Synonyms
- Deprecated S pneum19f IgG Ser-mCnc
- Category
- coagulation
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 82784
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Does This Test Measure?
IgG antibodies are a type of protein your immune system makes after encountering the COVID-19 virus. These antibodies are part of your body’s defense system and can remain in your blood for months or even years after infection. This test specifically looks for IgG antibodies against the spike protein of the SARS-CoV-2 virus, which is responsible for causing COVID-19. The result indicates whether your immune system has recognized and responded to the virus.
Why Might You Need This Test?
Healthcare providers may recommend this test if you have had COVID-19 symptoms, have been exposed to someone with COVID-19, or if you are recovering from a COVID-19 infection. It can also be used for screening in certain settings, such as before returning to work or travel, or for monitoring immunity in high-risk groups.
How Is This Test Performed?
A blood sample is drawn from a vein in your arm. The serum portion of the blood is then tested in a laboratory using an immunoassay method to detect the presence of IgG antibodies. The test does not measure the current viral load or active infection but rather past exposure.
What Are the Possible Results?
A positive result means your blood contains IgG antibodies to SARS-CoV-2, suggesting you likely had COVID-19 at some point and may have developed immunity. A negative result means no detectable IgG antibodies were found, indicating either no prior exposure or insufficient time since exposure for antibodies to develop. Results should be interpreted by a healthcare provider in the context of your medical history and symptoms.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
COVID-19 IgG Antibody Test
Frequently asked questions
How long do IgG antibodies last after COVID-19?
Can this test be used to confirm a current COVID-19 infection?
Does having IgG antibodies mean I’m immune to COVID-19?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy