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Antibody to Streptococcus pneumoniae (Serum or Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test detects antibodies in your blood that your immune system produces in response to *Streptococcus pneumoniae*, a common bacterial cause of pneumonia, ear infections, and other illnesses.

Quick summary

["Helps identify past or current immune response to pneumonia-causing bacteria."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
13131-8
Short code
Deprecated S pneum 1 Ab Ser-aCnc
Synonyms
Deprecated S pneum 1 Ab Ser-aCnc
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you’ve had symptoms of pneumonia, recurrent infections, or if you’re at higher risk for serious bacterial infections (e.g., due to weakened immunity, chronic conditions like asthma or heart disease, or recent travel to areas with high bacterial exposure). It may also be used to monitor immune response after vaccination or in cases where other tests are inconclusive.

What to Expect Before the Test

No special preparation is needed. A blood sample will be drawn from a vein, usually in your arm. You may feel a slight pinch, but it typically takes only a few minutes. If you’re on blood-thinning medication, let your provider know before the test.

What the Test Results Mean

Positive results indicate your immune system has recognized *Streptococcus pneumoniae* antibodies, suggesting exposure (either from infection or vaccination). Negative results mean no detectable antibodies were found, which may mean you haven’t been exposed recently or your immune system hasn’t mounted a response yet.

Common Reasons for Testing

This test is often used to diagnose or confirm infections caused by *Streptococcus pneumoniae*, assess immune function in patients with chronic illnesses, or evaluate the effectiveness of vaccines targeting this bacterium.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

High antibody levels may indicate past infection or vaccination success, but they don’t always correlate with immunity. Low or absent levels could prompt further investigation into immune deficiencies or recent exposure. Always discuss results with your provider—they’ll interpret them in the context of your health history and symptoms.

Short name

Strep pneumoniae Antibody

Frequently asked questions

What does a positive result mean for my health?
A positive result means your body has produced antibodies against *Streptococcus pneumoniae*, which may suggest past infection or vaccination. However, this doesn’t guarantee immunity—your provider will consider other factors like vaccination history, symptoms, and risk level to guide next steps.
Can I get this test at home?
No, this test requires a blood sample collected by a healthcare professional in a clinical setting. Home blood tests for antibodies are not standard for this specific analyte.
How long does it take to get results?
Results are typically available within 1–3 business days, depending on lab processing times. Your provider will contact you with the final report once it’s ready.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy