Total Immunoglobulin G (IgG) in Serum
This test measures the amount of Immunoglobulin G (IgG), a type of antibody in your blood. IgG helps protect your body from infections and diseases.
["IgG antibodies play a key role in long-term immunity and are often checked if you have concerns about immune function or recurrent infections."]
Key facts at a glance
- LOINC
- 40965-6
- Short code
- Deprecated S pneum20 IgG Ser-mCnc
- Synonyms
- Deprecated S pneum20 IgG Ser-mCnc
- Category
- coagulation
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 82784
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Does IgG Measure?
IgG is the most abundant antibody in your blood, produced by your immune system to fight off bacteria and viruses. It helps remember past infections and provides protection against future exposures. Levels can vary based on your immune health, age, and overall health status.
Why Might Your Doctor Order This Test?
Your doctor may order an IgG test if you have symptoms like frequent infections, unexplained illnesses, or if you’re being evaluated for conditions like HIV, autoimmune diseases, or immune deficiencies. It can also be part of routine monitoring for certain treatments.
How Is the Test Performed?
A blood sample is drawn from a vein, usually in your arm. The blood is then sent to a lab where it is tested for IgG levels using an immunoassay method, which detects the presence and concentration of antibodies.
What Are Common Results?
Results are typically reported as a concentration in grams per liter (g/L) or milligrams per deciliter (mg/dL). While reference ranges can vary by lab, lower than expected levels may suggest immune system issues, while higher levels might indicate chronic infections or other conditions.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
IgG Level
Frequently asked questions
Why might my IgG levels be checked regularly?
What does it mean if my IgG levels are low?
Can diet or lifestyle affect IgG levels?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy