Anti-Saccharomyces cerevisiae IgG (ASCA) Serum Immunoassay
This test measures the level of Immunoglobulin G (IgG) antibodies against *Saccharomyces cerevisiae* (a type of yeast) in your blood. It is often used to help diagnose conditions affecting the intestines, such as inflammatory bowel disease.
["ASCA IgG helps identify potential gut inflammation linked to certain autoimmune conditions."]
Key facts at a glance
- LOINC
- 47335-5
- Short code
- Deprecated S pneum22 IgG Ser IA-mCnc
- Synonyms
- Deprecated S pneum22 IgG Ser IA-mCnc
- Category
- coagulation
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- ia
- CPT
- 82784
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Is ASCA IgG Used For?
ASCA IgG antibodies may be detected in people with inflammatory bowel diseases like Crohn’s disease or ulcerative colitis. It can also be considered in cases where other tests are inconclusive or when evaluating autoimmune conditions that affect the gastrointestinal tract.
How Is This Test Performed?
A blood sample is taken from a vein, usually in your arm. The sample is then sent to a lab where it is tested using an immunoassay method to detect specific antibodies against the yeast antigen.
What Might High or Low Levels Indicate?
Elevated ASCA IgG levels may suggest an increased risk of inflammatory bowel disease or other autoimmune gastrointestinal conditions. However, results alone do not diagnose a condition—they are often used alongside other tests and clinical findings.
How Does This Test Fit Into My Care?
Your healthcare provider may order this test if you have symptoms like persistent diarrhea, abdominal pain, weight loss, or a family history of inflammatory bowel disease. It may also be used to monitor disease activity or guide treatment decisions.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance: ASCA IgG plays a role in identifying specific autoimmune responses in the gastrointestinal tract. While not definitive on its own, it can support a diagnosis of conditions like Crohn’s disease or ulcerative colitis by detecting antibodies linked to intestinal inflammation.
Short name
ASCA IgG
Frequently asked questions
Why was this test ordered for me?
What do my results mean?
Can I influence my results?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy