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IgG Antibody to Streptococcus pneumoniae (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of antibodies (IgG) your body produces in response to Streptococcus pneumoniae, a common bacterial cause of pneumonia, meningitis, and other infections.

Quick summary

["Helps assess immunity to pneumococcal bacteria after vaccination or natural exposure."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
47491-6
Short code
Deprecated S pneum22 IgG sp1 Ser-mCnc
Synonyms
Deprecated S pneum22 IgG sp1 Ser-mCnc
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Your doctor has ordered this blood test to learn more about your overall health and to help find, diagnose, or monitor a medical condition. The results provide important information that guides decisions about your ongoing care and treatment plan.

Your healthcare provider may order this test if you have a history of pneumococcal infections, are at high risk for complications (e.g., due to weakened immune system), or if you’ve received pneumococcal vaccination to confirm immune response.

Before the test, you can eat and drink as usual because no special preparation is needed. Try to arrive wearing a shirt with loose sleeves so your arm is easy to access, and tell the staff about any medications or supplements you currently take.

No special preparation is needed. A blood sample is drawn from a vein, usually in your arm. The sample is processed to measure IgG antibody levels.

Your results will be compared with standard reference ranges to show whether your values fall within the expected levels. Results in the normal range usually mean there is no sign of the condition being tested, while values outside the range may require follow-up with your doctor.

Results indicate whether your immune system has produced detectable antibodies against pneumococcal bacteria. Elevated levels suggest immunity, while low or absent levels may indicate insufficient response to vaccination or prior infection.

Abnormal results can come from many everyday factors, such as a recent illness, stress, dehydration, or certain medications. Sometimes an unusual result is only temporary, so your doctor may repeat the test before recommending any further evaluation or treatment.

Low IgG levels may occur after vaccination failure, chronic illness, or immune deficiencies. High levels could reflect recent infection or overactive immune response.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical significance: This test is primarily used to evaluate immune response to pneumococcal vaccination or to diagnose immune-related risks for pneumococcal infections in high-risk patients. It does not replace other diagnostic tests for active infections but can guide preventive strategies.

Short name

Anti-pneumococcal IgG

Frequently asked questions

Will I need to fast before this test?
No fasting is required for this test. Your blood sample can be drawn at any time of day, so you may schedule your appointment whenever it is most convenient for you.
What does a low IgG level mean?
A low IgG level may mean your body isn’t producing enough antibodies to protect against pneumococcal bacteria, which could increase infection risk. Discuss with your provider if you’ve received pneumococcal vaccine.
How long does it take to get results?
Results are typically available within 1–3 business days, depending on lab processing times.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy