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IgG Antibody to Streptococcus pneumoniae (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of antibodies in your blood that target *Streptococcus pneumoniae*, a common bacteria responsible for pneumonia, meningitis, and other infections.

Quick summary

["Helps assess immune response to pneumococcal vaccination or past infection."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
47492-4
Short code
Deprecated S pneum22 IgG sp2 Ser-mCnc
Synonyms
Deprecated S pneum22 IgG sp2 Ser-mCnc
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have a history of pneumococcal infections, are at high risk (e.g., due to weakened immune system), or if you’ve received pneumococcal vaccination to monitor your immune response.

What to Expect Before the Test

A simple blood draw is typically used. No special preparation is needed, but inform your provider about any medications or conditions that could affect results.

How the Results Are Interpreted

Results are compared to general reference ranges for healthy adults. Low levels may suggest poor immune response to vaccination or past infection, while higher levels could indicate active immunity.

Common Causes of Abnormal Results

Low levels may occur in people with immune deficiencies, those who haven’t responded well to vaccination, or those with recent pneumococcal infections. High levels may reflect natural immunity or prior exposure.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Monitoring Immunity and Risk Assessment

Short name

Anti-pneumococcal IgG

Frequently asked questions

Could I get this test if I’ve had pneumonia recently?
Yes, but results may not reflect recent infection. This test is more useful for evaluating long-term immunity after vaccination or past exposure.
What if my results are below the expected range?
Your provider may recommend additional vaccines, immune support measures, or further evaluation of your immune system if levels are significantly low.
Is this test the same as a pneumococcal vaccine antibody test?
Yes, it measures antibodies against *Streptococcus pneumoniae* (pneumococcus), which is the target of pneumococcal vaccines like Prevnar or Pneumovax.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy