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Antibody to Streptococcus pneumoniae (Serum) – Qualitative

Published: August 9, 2026Updated: August 16, 2026

This test checks for antibodies in your blood that may indicate a past or current infection with *Streptococcus pneumoniae*, a common bacterial cause of pneumonia, ear infections, and other respiratory illnesses.

Quick summary

["A positive result may suggest recent exposure or infection by this bacterium."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
13166-4
Short code
Deprecated S pneum23 Ab Ser-aCnc
Synonyms
Deprecated S pneum23 Ab Ser-aCnc
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

This qualitative test detects the presence of antibodies against *Streptococcus pneumoniae* in your serum. Antibodies are proteins your immune system produces in response to infection. If your body has encountered this bacteria before or is fighting an active infection, these antibodies will be present.

Why It’s Done

Doctors may order this test if you have symptoms of pneumonia, sinusitis, or other respiratory infections, especially if you’re at higher risk (e.g., young children, elderly adults, or those with weakened immune systems). It can also help confirm a diagnosis in certain clinical settings.

How the Test Works

A blood sample is taken, and the serum is analyzed to detect specific antibodies against *Streptococcus pneumoniae*. The result is reported as positive or negative, indicating whether antibodies were found.

What the Results Mean

A **positive** result suggests your immune system has recognized *Streptococcus pneumoniae* (either from past infection or vaccination). A **negative** result means no detectable antibodies were found at the time of testing.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

S. pneumoniae Antibody Screen

Frequently asked questions

Why might this test be important?
This test helps clinicians assess exposure risk, monitor immune response to vaccination, or guide treatment decisions for suspected *Streptococcus pneumoniae* infections. It’s particularly useful in diagnosing conditions where bacterial pneumonia is suspected but other tests are inconclusive.
What does a positive result mean for my health?
A positive result doesn’t always mean you’re currently sick—it could reflect past infection or vaccination. If you’re experiencing symptoms like fever, cough, or difficulty breathing, discuss your results with your doctor to explore further testing or treatment options.
Could this test affect my vaccination schedule?
Yes, if you’re receiving pneumococcal vaccines, this test may be used to monitor immune response or confirm vaccination effectiveness. Follow your healthcare provider’s guidance on timing and follow-up.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy