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Antibody to Pneumocystis jirovecii (IgG) – Serum

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence of antibodies against the fungus *Pneumocystis jirovecii*, which can cause a lung infection called Pneumocystis pneumonia (PCP). It helps identify past exposure or infection, often used in patients at high risk, such as those with weakened immune systems.

Quick summary

["This test helps doctors assess risk for or track past exposure to a lung infection linked to weakened immunity."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
27119-7
Short code
Deprecated S pneum23 Ab sp2 Ser-mCnc
Synonyms
Deprecated S pneum23 Ab sp2 Ser-mCnc
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order this test if you have symptoms like cough, shortness of breath, or fever and are at higher risk for PCP. High-risk groups include people with HIV/AIDS, those undergoing chemotherapy, transplant recipients, or those with certain immune disorders. It’s also used to monitor patients who have already been treated for PCP to ensure they no longer carry the infection.

What to Expect Before the Test

No special preparation is needed. You’ll have a small needle inserted into your arm or vein to draw blood. The process usually takes a few minutes. If you’re nervous, let your healthcare provider know—they can help make it more comfortable.

What the Results Mean

Positive results indicate the presence of antibodies, suggesting past exposure to *Pneumocystis jirovecii*. However, antibodies alone don’t always mean you currently have an active infection. Your doctor will consider your medical history, symptoms, and other test results to interpret the results accurately.

Possible Side Effects

Most people experience only mild discomfort or bruising at the injection site. Rarely, you might feel lightheaded or have a slight reaction to the needle. If you experience severe pain, swelling, or signs of infection (like redness or fever), contact your doctor right away.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Pneumocystis jirovecii IgG Antibody

Frequently asked questions

How often should I get this test?
Your doctor will determine the frequency based on your medical condition, risk factors, and treatment history. For example, patients with HIV/AIDS may need testing more often during or after treatment for PCP.
What does a positive result mean for my health?
A positive result means your body has produced antibodies against *Pneumocystis jirovecii*, but it doesn’t always mean you’re currently infected. It may indicate past exposure or immunity. Your doctor will discuss next steps, such as further testing or monitoring, depending on your overall health and symptoms.
Can I still get PCP even if my antibody test is negative?
Yes. Antibody tests measure past exposure, not current infection. If you’re at high risk (e.g., HIV/AIDS, chemotherapy), your doctor may still recommend other tests or preventive measures, like antibiotics, to protect you from PCP.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy