IgG Substance Concentration in Serum (Qualitative or Screening)
This test measures the presence or level of Immunoglobulin G (IgG), a type of antibody in your blood. IgG is important for long-term immunity.
["IgG helps protect your body from infections and diseases over time."]
Key facts at a glance
- LOINC
- 22548-2
- Short code
- Deprecated S pneum23 IgG Ser-aCnc
- Synonyms
- Deprecated S pneum23 IgG Ser-aCnc
- Category
- coagulation
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 82784
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What IgG Testing Measures
IgG is the most abundant antibody in your blood and plays a key role in defending against bacteria and viruses. This test helps determine if your immune system is producing enough IgG, which is crucial for fighting infections long-term. It may be used to check for immune deficiencies, monitor treatment responses, or evaluate immune responses in certain conditions.
Why You Might Need This Test
A healthcare provider may recommend this test if you have symptoms of a weakened immune system, such as frequent infections, recurrent illnesses, or if you’re being treated for an immune-related condition. It can also be part of a broader evaluation for conditions like HIV, autoimmune diseases, or congenital immune disorders.
Sample Collection and Preparation
A blood sample is drawn from a vein, usually in your arm. The blood is then processed to separate the serum (the liquid part without clots). This serum is tested for IgG levels or presence.
Test Results and Interpretation
Results are typically reported as qualitative (positive/negative) or quantitative (levels of IgG). A qualitative test tells if IgG is present, while a quantitative test provides a specific measurement. Interpretation depends on clinical context, such as your medical history and symptoms.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Low IgG levels may indicate an immune deficiency, where your body struggles to fight infections effectively. High levels might be seen in chronic infections, certain autoimmune diseases, or as a side effect of some treatments. This test helps guide treatment plans and monitor immune health over time.
Short name
IgG Screening (Serum)
Frequently asked questions
What does a positive or negative result mean?
How often should I get this test?
Can diet or lifestyle affect IgG levels?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy