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Immunoglobulin G (IgG) in Serum, Mass Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of Immunoglobulin G (IgG), a type of antibody in your blood. IgG helps protect your body from infections and diseases.

Quick summary

["IgG helps fight infections and supports long-term immunity."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
30495-6
Short code
Deprecated S pneum23 IgG sp2 Ser-mCnc
Synonyms
Deprecated S pneum23 IgG sp2 Ser-mCnc
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

IgG is one of the most common types of antibodies in your blood. It plays a key role in defending your body against bacteria and viruses. This test helps doctors assess your immune system’s ability to produce antibodies, which is important for fighting infections and maintaining immunity over time.

Why Might You Need This Test?

Your doctor may order this test if you have symptoms of a weakened immune system, such as frequent infections, unusual fatigue, or if you’re being treated for conditions like autoimmune diseases, certain cancers, or after receiving certain medical treatments (e.g., chemotherapy). It can also be part of monitoring for conditions like HIV or other immune-related disorders.

What to Expect Before the Test

No special preparation is usually needed for this blood test. You may be asked to fast before the test if it’s part of a larger panel, but this is not always required for IgG alone. Bring any medications or supplements you’re taking to your appointment.

What to Expect During the Test

A healthcare professional will draw blood from a vein in your arm. You may feel a slight pinch or discomfort, but it usually only takes a few minutes. The blood sample will be sent to a lab for analysis.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

IgG Level

Frequently asked questions

Why might my IgG levels be checked regularly?
Regular IgG monitoring may be recommended if you have a chronic condition that affects your immune system, such as HIV/AIDS, certain cancers, or after receiving treatments like chemotherapy or stem cell transplants. Your doctor may also check IgG levels if you have symptoms like frequent infections, unusual bruising, or slow wound healing.
What do my IgG results mean?
Results are typically reported as a mass concentration (often in grams per liter). Your doctor will compare your results to what’s considered normal for your age and health status. If your levels are outside the expected range, further testing or evaluation may be needed to understand the cause.
Can diet or lifestyle affect IgG levels?
While diet and lifestyle factors like nutrition and stress can influence overall immune function, they generally do not directly affect IgG levels. However, maintaining a balanced diet rich in vitamins and minerals can support your immune system’s ability to function properly.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy