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Immunoglobulin G (IgG) in Serum

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of Immunoglobulin G (IgG), a type of antibody in your blood. IgG helps protect your body from infections and diseases.

Quick summary

["IgG helps fight infections and supports long-term immunity."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
47340-5
Short code
Deprecated S pneum34 IgG sp2 Ser IA-mCnc
Synonyms
Deprecated S pneum34 IgG sp2 Ser IA-mCnc
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Immunoglobulin G (IgG)?

IgG is the most common type of antibody in your blood. Antibodies are proteins that help your immune system recognize and fight off harmful substances like bacteria and viruses. IgG is particularly important for providing long-term immunity after you recover from an infection or receive a vaccine.

Why Might You Need This Test?

Doctors may order an IgG test to check for low or high levels, which can indicate conditions like immune deficiencies, chronic infections, or certain autoimmune diseases. It may also be used to monitor treatment responses in patients with immune-related conditions.

Common Reasons for Testing

Common reasons include diagnosing or monitoring immune system disorders, assessing immune response after vaccination, evaluating chronic illnesses (e.g., HIV, hepatitis), or checking for signs of malnutrition or malabsorption.

What to Expect Before the Test

No special preparation is usually needed. You may have a small needle inserted into your arm to draw blood. If you’re nervous, let your healthcare provider know so they can help.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Low IgG levels may suggest an immune deficiency, chronic infections, or conditions like celiac disease or malabsorption. High IgG levels can sometimes indicate chronic infections, autoimmune disorders, or certain cancers. Monitoring IgG levels helps guide treatment decisions for immune-related conditions.

Short name

IgG Level

Frequently asked questions

What does an abnormal IgG result mean?
An abnormal IgG result doesn’t have a single interpretation—it depends on your overall health, symptoms, and medical history. Your doctor will discuss the results with you and may recommend further testing or treatments.
How often should I get this test?
Your doctor will determine how often you need this test based on your medical needs. Some people may need it once, while others may need it regularly to monitor their condition.
Can diet or lifestyle affect IgG levels?
Diet and lifestyle factors like nutrition, infections, or chronic illnesses can influence IgG levels. Avoiding infections and maintaining a balanced diet may support healthy immune function, but this test alone won’t show lifestyle impacts.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy