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Pneumococcal Antigen in Serum (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence of pneumococcal bacteria antigens in your blood serum, which can help detect early signs of pneumococcal infections.

Quick summary

["Helps identify pneumococcal infections in bloodstream quickly for prompt treatment."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
26875-5
Short code
Deprecated S pneum4 Ab Ser-mCnc
Synonyms
Deprecated S pneum4 Ab Ser-mCnc
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may order this test if you have symptoms like fever, chills, or confusion that could indicate a serious bacterial infection, particularly if you have a weakened immune system or underlying health conditions. It may also be used in certain clinical settings to monitor for infection in high-risk patients.

How the Test Works

The test detects specific antigens from *Streptococcus pneumoniae* (pneumococcus) bacteria in your serum. These antigens are fragments of the bacterial cell wall that the immune system recognizes. The test uses a sensitive method to measure their concentration, helping identify infection before symptoms become severe.

Sample Collection and Preparation

A blood sample is drawn from a vein, typically in your arm. The blood is then processed to separate serum (the liquid part after clotting), which is sent to the lab for testing. This test is not typically done on urine or other body fluids.

What to Expect Before the Test

No special preparation is needed for this test. You may have some mild discomfort or bruising at the injection site, but this usually resolves quickly. If you are on blood-thinning medication, let your provider know before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Serum Pneumococcal Antigen

Frequently asked questions

What does a positive result mean?
A positive result indicates the presence of pneumococcal antigens in your blood, strongly suggesting an active infection caused by *Streptococcus pneumoniae*. This finding should prompt immediate medical evaluation and treatment with appropriate antibiotics.
What does a negative result mean?
A negative result means no detectable pneumococcal antigens were found in your serum at the time of testing. However, this does not rule out infection entirely, especially if symptoms are mild or if the infection is not yet in the bloodstream. Further testing or follow-up may be recommended.
How soon can I expect results?
Results are typically available within 24 to 48 hours, depending on lab processing times. Your healthcare provider will discuss the results with you and determine the next steps, such as starting antibiotics or additional testing.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy