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Serum or plasma mass concentration of antimicrobial peptides (e.g., defensins, cathelicidins)

Published: August 9, 2026Updated: August 16, 2026

This test measures certain natural proteins in your blood that help fight infections. These proteins are part of your body’s immune defense system.

Quick summary

["Understanding your immune response to infections through blood protein levels."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
27964-6
Short code
Deprecated S pneum6+26 Ab Ser-mCnc
Synonyms
Deprecated S pneum6+26 Ab Ser-mCnc
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms of frequent infections, immune system disorders, or if you’re undergoing treatment for conditions like chronic inflammation or autoimmune diseases. It can also help monitor immune function in certain medical conditions.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for a few hours if the test involves a specific type of specimen. Bring any medications you’re currently taking to your appointment.

What the Test Involves

A healthcare professional will draw blood from a vein in your arm. The blood sample will be sent to a lab for analysis. The test measures the mass concentration of antimicrobial peptides, which are proteins that help protect your body against harmful bacteria and viruses.

What the Results Mean

Results may indicate whether your immune system is producing adequate levels of these proteins. Abnormal levels could suggest an overactive or underactive immune response, which may require further evaluation by your doctor.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Low levels of antimicrobial peptides might be linked to increased susceptibility to infections, while elevated levels could point to chronic inflammation, autoimmune conditions, or other immune-related disorders. This test can help guide treatment plans for managing these conditions.

Short name

Antimicrobial peptide levels

Frequently asked questions

What does a low level of antimicrobial peptides mean?
A low level may indicate a weakened immune response, potentially due to conditions like HIV/AIDS, certain cancers, or long-term use of immunosuppressive medications. Your doctor will discuss further actions based on your overall health and symptoms.
What does a high level of antimicrobial peptides mean?
High levels might suggest chronic inflammation, autoimmune diseases, or other conditions that cause persistent immune activation. This could also be a normal response in some situations, so your doctor will interpret results in the context of your medical history.
Can lifestyle changes affect these test results?
Yes, lifestyle factors such as diet, exercise, and stress levels can influence immune function. Maintaining a balanced diet rich in nutrients and staying hydrated may support your immune system, but results should always be reviewed by your healthcare provider.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy