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Aspergillus antigen (serum/plasma) – Quantitative

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence of antibodies to *Aspergillus*, a type of mold that can cause infections in the lungs or other parts of the body. It helps doctors check for exposure to this fungus, especially in people with weakened immune systems or lung conditions.

Quick summary

["Helps detect fungal exposure and assess immune response to *Aspergillus* mold."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
13134-2
Short code
Deprecated S pneum8 Ab Ser-aCnc
Synonyms
Deprecated S pneum8 Ab Ser-aCnc
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order this test if you have symptoms like persistent cough, wheezing, or lung problems, or if you’ve been exposed to mold environments. It’s also used in people with conditions like HIV/AIDS, cancer, or lung diseases (e.g., cystic fibrosis) that increase risk for fungal infections.

What to Expect Before the Test

No special preparation is needed. You’ll provide a blood sample, usually drawn from your arm. The test looks for antibodies in your serum or plasma, which develop after your body has been exposed to *Aspergillus* antigens.

What the Results Mean

Positive results suggest your immune system has detected *Aspergillus* exposure, possibly indicating an infection or past exposure. Negative results mean no detectable antibodies were found. Results alone don’t confirm a diagnosis; they’re used alongside other tests and symptoms.

Common Causes of Abnormal Results

Elevated antibody levels may occur after exposure to mold in air, water, or soil. They can also appear in people with chronic lung diseases or immune disorders. False positives are rare but possible if you’ve had a previous *Aspergillus* infection or exposure.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Aspergillus Antibody Test

Frequently asked questions

How soon after exposure can antibodies appear?
Antibodies typically develop within weeks to months after exposure, depending on the duration and severity of contact. Some people may never develop detectable levels, especially if their immune system is compromised.
Can this test replace other diagnostic tests like cultures?
No, this test is a screening tool. Doctors often use it alongside other tests, such as chest X-rays, cultures, or fungal-specific tests, to confirm a diagnosis of *Aspergillus* infection.
Is this test covered by insurance?
Coverage depends on your insurance plan and medical reason for testing. Check with your provider or insurance company to confirm if this test is included under your benefits.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy