Serum Protein Electrophoresis (Qualitative)
This test measures the different types of proteins in your blood serum using electrophoresis, a technique that separates proteins based on size and charge.
["Helps identify abnormal protein patterns that may signal conditions like multiple myeloma, liver disease, or other disorders."]
Key facts at a glance
- LOINC
- 13149-0
- Short code
- Deprecated S pneum8 Ab sp1 Ser-aCnc
- Synonyms
- Deprecated S pneum8 Ab sp1 Ser-aCnc
- Category
- coagulation
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
Electrophoresis separates blood proteins into fractions, such as albumin, globulins, and other components, which can reveal imbalances or unusual patterns. This is typically done using a gel or paper medium and an electric current.
Why It’s Done
Doctors may order this test to diagnose or monitor conditions like multiple myeloma, lymphoma, liver disease, kidney disease, or certain autoimmune disorders. It can also help assess protein disorders or screen for hidden blood diseases.
Sample Collection and Preparation
A blood sample is drawn from a vein, usually in your arm. The serum (liquid part after clotting) is then prepared for analysis by applying it to a gel or paper substrate and running it through an electric field to separate proteins.
Common Conditions Monitored
This test helps detect abnormal protein levels that may indicate conditions such as multiple myeloma (cancer of plasma cells), benign monoclonal gammopathy, liver or kidney disease, or other metabolic disorders.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Abnormal electrophoresis results can signal underlying health issues, such as the presence of monoclonal proteins (spikes) that may require further testing for conditions like plasma cell disorders. Low albumin levels may indicate liver or kidney problems, while high globulin levels could suggest immune system or inflammatory conditions. Always discuss results with your healthcare provider for accurate interpretation.
Short name
Protein Electrophoresis
Frequently asked questions
How long does it take to get results from this test?
Can I eat or drink anything before this test?
Is there any risk or discomfort with this blood draw?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy