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IgG Antibody to Streptococcus pneumoniae (Serum)

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of antibodies your body produces in response to the bacteria *Streptococcus pneumoniae*, which can cause serious infections like pneumonia.

Quick summary

["Helps assess immune response to pneumococcal vaccination or infection risk."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
25277-5
Short code
Deprecated S pneum8 IgG 2:1 Ser-Rto
Synonyms
Deprecated S pneum8 IgG 2:1 Ser-Rto
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Your immune system produces antibodies like IgG to fight off infections. This test checks if your body has developed these antibodies against *Streptococcus pneumoniae*, a common cause of pneumonia, ear infections, and other illnesses. It may be used to evaluate vaccination effectiveness or monitor immune function in certain conditions.

How the Test Works

A small blood sample is drawn from your arm. The serum (liquid part of blood) is tested for the presence of IgG antibodies specific to *Streptococcus pneumoniae*. The result indicates whether your immune system has recognized and responded to this bacteria.

When You Might Need This Test

Your healthcare provider may order this test if you’ve had a pneumococcal vaccine, have a weakened immune system, or are at higher risk for pneumococcal infections (e.g., due to chronic health conditions). It can also help diagnose or monitor conditions like chronic granulomatous disease or other immune disorders.

What to Expect Before the Test

No special preparation is usually needed. You may be asked to fast for 8–12 hours before the test if your doctor specifies, but this is rare for this type of antibody test. Wear comfortable clothing and bring your ID if you’re a new patient.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Anti-pneumococcal IgG

Frequently asked questions

What does a low or high IgG level mean?
A low IgG level against *Streptococcus pneumoniae* may indicate poor immune response to vaccination or an underlying immune deficiency. A high level suggests your body has mounted an immune response, either after infection or vaccination. Always discuss results with your doctor, as they’ll consider your medical history and symptoms.
How long does it take to get results?
Results are typically available within 2–5 business days, depending on your lab’s processing time. Your doctor will explain the meaning of your specific result in the context of your health.
Can I get this test at home?
No, this test requires a blood sample collected by a healthcare professional in a clinical setting. Home blood tests for antibodies are not standard for this specific analyte.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy