Skip to content

Immunoglobulin G (IgG) in Serum

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of Immunoglobulin G (IgG), a type of antibody in your blood. IgG helps protect your body from infections and diseases.

Quick summary

["IgG levels can indicate immune function and response to infections or treatments."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
40920-1
Short code
Deprecated S pneum8 IgG Ser IA-mCnc
Synonyms
Deprecated S pneum8 IgG Ser IA-mCnc
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

IgG is the most abundant antibody in your blood and plays a key role in long-term immunity. It helps your immune system fight off bacteria and viruses by marking them for destruction. Measuring IgG helps doctors assess your immune system’s strength and identify issues like low immunity, infections, or certain immune disorders.

Why Might You Need This Test?

Your doctor may order an IgG test if you have symptoms of a weakened immune system, such as frequent infections, slow healing of wounds, or unexplained fatigue. It may also be used to monitor immune responses to treatments like chemotherapy, vaccines, or medications that affect immunity.

Sample Collection and Preparation

A blood sample is taken from a vein in your arm. You may feel a small pinch when the needle is inserted, but the procedure is quick. The blood is then sent to a lab for analysis. No special preparation is needed, but avoid eating or drinking for a few hours before the test if instructed.

What to Expect After the Test

After the blood is drawn, you can return to your normal activities. You may experience mild bruising, swelling, or discomfort at the injection site, which usually goes away within a day or two. Follow-up instructions from your doctor will guide you on next steps, such as when to expect results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Low IgG levels may suggest an immune deficiency, such as common variable immunodeficiency (CVID), which can make you more prone to infections. High IgG levels can sometimes indicate chronic infections, autoimmune diseases, or certain types of cancer. Your doctor will interpret the results in the context of your overall health and symptoms.

Short name

IgG Level

Frequently asked questions

How Long Does It Take to Get Results?
Results are typically available within 1 to 3 business days, depending on your lab and healthcare provider. You’ll usually receive a call or letter with your results, but always confirm with your doctor’s office for the most accurate timeline.
Can IgG Levels Change Over Time?
Yes, IgG levels can fluctuate due to infections, vaccinations, pregnancy, or certain medications. If your levels are abnormal, your doctor may recommend retesting after a few months to monitor changes.
What If My IgG Level Is Abnormal?
If your IgG level is low, your doctor may recommend additional tests or treatments to strengthen your immune system. If it’s high, further evaluation may be needed to determine the underlying cause, such as infections or autoimmune conditions. Always discuss your results with your healthcare provider for personalized guidance.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy