Immunoglobulin G (IgG) in Serum
This test measures the amount of Immunoglobulin G (IgG), a type of antibody in your blood. IgG helps protect your body from infections and diseases.
["IgG levels can indicate immune function and response to infections or treatments."]
Key facts at a glance
- LOINC
- 40920-1
- Short code
- Deprecated S pneum8 IgG Ser IA-mCnc
- Synonyms
- Deprecated S pneum8 IgG Ser IA-mCnc
- Category
- coagulation
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- ia
- CPT
- 82784
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Does This Test Measure?
IgG is the most abundant antibody in your blood and plays a key role in long-term immunity. It helps your immune system fight off bacteria and viruses by marking them for destruction. Measuring IgG helps doctors assess your immune system’s strength and identify issues like low immunity, infections, or certain immune disorders.
Why Might You Need This Test?
Your doctor may order an IgG test if you have symptoms of a weakened immune system, such as frequent infections, slow healing of wounds, or unexplained fatigue. It may also be used to monitor immune responses to treatments like chemotherapy, vaccines, or medications that affect immunity.
Sample Collection and Preparation
A blood sample is taken from a vein in your arm. You may feel a small pinch when the needle is inserted, but the procedure is quick. The blood is then sent to a lab for analysis. No special preparation is needed, but avoid eating or drinking for a few hours before the test if instructed.
What to Expect After the Test
After the blood is drawn, you can return to your normal activities. You may experience mild bruising, swelling, or discomfort at the injection site, which usually goes away within a day or two. Follow-up instructions from your doctor will guide you on next steps, such as when to expect results.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Low IgG levels may suggest an immune deficiency, such as common variable immunodeficiency (CVID), which can make you more prone to infections. High IgG levels can sometimes indicate chronic infections, autoimmune diseases, or certain types of cancer. Your doctor will interpret the results in the context of your overall health and symptoms.
Short name
IgG Level
Frequently asked questions
How Long Does It Take to Get Results?
Can IgG Levels Change Over Time?
What If My IgG Level Is Abnormal?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy