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Carbon Monoxide in Blood (Carboxyhemoglobin)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of carbon monoxide bound to your red blood cells, which can indicate exposure to smoke, fumes, or other carbon monoxide sources. It’s often used in emergency settings or for monitoring occupational hazards.

Quick summary

["Helps assess exposure to carbon monoxide, which can be dangerous if levels are high."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
29318-3
Short code
Deprecated S pneumB Ag Ser Ql LA
Synonyms
Deprecated S pneumB Ag Ser Ql LA
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
la
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may order this test if you’ve been exposed to smoke, vehicle exhaust, or industrial fumes. It’s also used in cases of suspected carbon monoxide poisoning, especially in smoke inhalation or occupational settings. Some hospitals check newborns for CO exposure during delivery.

What to Expect Before the Test

No special preparation is needed. You’ll likely have a small needle inserted into your arm to draw blood. If you’re a smoker or have recent exposure to carbon monoxide, your provider may discuss this with you beforehand.

What the Results Mean

High levels of carbon monoxide in your blood can block oxygen from reaching your organs. Mild exposure may cause headaches or dizziness, while severe exposure can lead to unconsciousness or even death. Your provider will interpret results based on your symptoms, exposure history, and overall health.

Common Causes of Abnormal Results

Elevated carbon monoxide levels can result from smoking cigarettes, pipes, or cigars; exposure to vehicle exhaust; heating systems with poor ventilation; or industrial environments. Natural sources like certain plants (e.g., some mushrooms) can also contribute, though this is rare.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

COHb (Blood Carbon Monoxide Level)

Frequently asked questions

What does a high level of carbon monoxide in my blood mean?
A high level may indicate recent exposure to carbon monoxide, which can impair oxygen delivery to your body. This could be due to smoking, vehicle fumes, or other sources. Your provider will review your symptoms and medical history to determine if further action is needed, such as treatment or monitoring.
How often should I get this test?
This test is typically done only when needed, such as after suspected exposure or during certain medical evaluations. Your provider will decide how often you need it based on your situation, such as occupational risks or recent symptoms.
Can I prevent carbon monoxide poisoning?
Yes! To reduce risk, use carbon monoxide detectors in your home, avoid running cars or generators indoors, and ensure proper ventilation in garages or workshops. If you smoke, consider quitting to lower your exposure.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy