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Pneumococcal DNA Detection by PCR (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test checks for genetic material from *Streptococcus pneumoniae* (pneumococcus) bacteria in your blood or plasma, often used to evaluate suspected bacterial pneumonia or sepsis.

Quick summary

["Looks for bacterial DNA to help diagnose serious infections."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
49611-7
Short code
Deprecated S pneum DNA XXX PCR
Synonyms
Deprecated S pneum DNA XXX PCR
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

This test is done to help your health care provider gather important information about your health. It can be used to look for a specific condition, confirm or rule out a diagnosis, or monitor how well a current treatment is working over time.

Your healthcare provider may order this test if you have symptoms like high fever, difficulty breathing, or signs of infection that could be caused by pneumococcal bacteria. It’s particularly useful in diagnosing conditions like pneumonia or bloodstream infections (sepsis).

The test works by measuring specific markers or signals in the sample or reading taken from your body. These measurements are then compared with established reference ranges so your provider can tell whether your results fall within expected limits.

Before the test, follow any instructions your provider gives you, such as fasting, avoiding certain foods or drinks, or pausing specific medications. Arrive on time, wear comfortable clothing, and tell the staff about any allergies, medications, or medical conditions you have.

Your results are interpreted by comparing your values with typical reference ranges. A result within the normal range usually suggests no problem was found, while an abnormal result does not always mean disease; it simply means your provider should take a closer look.

Possible results include normal, abnormal, or inconclusive findings. If your results are normal, your provider may recommend routine monitoring. If they are abnormal, next steps may include repeat testing, additional lab work or imaging, a referral to a specialist, or starting or adjusting treatment.

False results can happen for several reasons, including recent illness, certain medications or supplements, improper sample collection or handling, eating or drinking when you were told to fast, or testing at the wrong time relative to your symptoms or treatment.

Follow up with your provider as directed to review your results, usually within one to two weeks or sooner if advised. Contact the office right away if your symptoms get worse, if you develop new symptoms, or if you have questions about what your results mean.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Pneumococcal DNA PCR

Frequently asked questions

How long does it take to get results?
Results are typically available within 24 to 48 hours, depending on lab processing times. Your provider will contact you once results are ready.
Can I eat or drink before this test?
No special diet or fasting is required. You may have a light snack if needed, but avoid heavy meals before the blood draw.
Is there any risk or discomfort with this test?
The blood draw may cause mild discomfort or bruising at the site, but it’s generally safe. Rarely, there could be allergic reactions to the needle or blood collection process, though this is uncommon.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy