Skip to content

Streptococcus pneumoniae Antibody Screening (Serum/Plasma) by Immunoassay

Published: August 9, 2026Updated: August 16, 2026

This test checks for antibodies in your blood that your immune system produces in response to *Streptococcus pneumoniae* (pneumonia bacteria). It helps determine if your body has been exposed to this germ, which can cause serious infections like pneumonia.

Quick summary

["This test helps doctors assess past exposure to pneumonia bacteria and guide treatment decisions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
74737-8
Short code
Deprecated S pneumoniae gryB Bld Pos Ql Prb Mag
Synonyms
Deprecated S pneumoniae gryB Bld Pos Ql Prb Mag
Category
coagulation
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-mag-capture
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your doctor may recommend this test if you’ve had symptoms of pneumonia, have a history of respiratory infections, or are at higher risk for complications from *Streptococcus pneumoniae*. It’s also sometimes used in screening for people in close contact with those who have pneumonia.

How the Test Works

A small blood sample is taken from your arm. The serum or plasma is then tested using an immunoassay method to detect specific antibodies against *Streptococcus pneumoniae*. This identifies whether your immune system has recognized and responded to the bacteria.

What to Expect Before the Test

No special preparation is needed. You can eat, drink, or take medications as usual. If you’re on blood-thinning medication, let your doctor know before the test.

What to Expect During the Test

You’ll lie down on a table while a healthcare provider inserts a needle into a vein in your arm. A small amount of blood is drawn into a vial or tube. The process usually takes a few minutes. You may feel a brief pinch, but most people find it quick and not very uncomfortable.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Positive results indicate past exposure to *Streptococcus pneumoniae*, meaning your immune system has developed antibodies to fight it. This can help confirm a diagnosis of pneumonia, guide vaccination decisions, or assess risk for recurrent infections. However, a negative result does not rule out infection—other tests or clinical evaluation may be needed.

Short name

Strep pneumoniae Antibody Screen

Frequently asked questions

Does this test show if I currently have pneumonia?
No, this test only detects antibodies from past exposure. If you’re currently sick with pneumonia, your doctor may order additional tests, like a chest X-ray or culture, to diagnose the infection.
Can I get vaccinated instead of having this test?
Yes! If your doctor suspects *Streptococcus pneumoniae* exposure, vaccination (e.g., pneumococcal vaccine) is often recommended as a safer and more direct way to prevent infection. This test is typically used for research, screening, or monitoring rather than routine care.
How long will it take to get my results?
Results are usually available within 1–3 business days, depending on your lab. Your doctor will discuss them with you during your follow-up visit.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy