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Pneumococcal DNA Serotype Identification by Nucleic Acid Probe

Published: August 9, 2026Updated: August 16, 2026

This test detects specific genetic material (DNA) from *Streptococcus pneumoniae* (pneumococcus) bacteria to identify which serotype you may have. It helps determine the type of bacteria causing your infection.

Quick summary

["This test helps doctors choose the best treatment for pneumonia or other pneumococcal infections."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
86503-0
Short code
Deprecated S pneum serotype DNA XXX NAA+probe
Synonyms
Deprecated S pneum serotype DNA XXX NAA+probe
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order this test if you have symptoms of pneumonia (such as cough, fever, or difficulty breathing) and suspect pneumococcal infection. It’s particularly useful in certain groups, like those with weakened immune systems or chronic health conditions.

How the Test Works

A small sample of your respiratory secretions (like sputum or nasal swab) is collected and analyzed for pneumococcal DNA. A specialized probe detects the unique genetic sequences of different serotypes of pneumococcus, helping identify the exact strain.

Sample Collection and Preparation

A healthcare provider will collect a sample (e.g., sputum, nasal swab, or sometimes blood) to send to the lab. The lab processes the sample to extract DNA, then applies the probe to identify serotypes.

What to Expect After the Test

Results are typically available within 24–48 hours. Your doctor will discuss the findings and recommend treatment based on the identified serotype.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: This test is critical for guiding antibiotic selection. Knowing the exact serotype allows doctors to choose targeted treatments (e.g., vaccines or specific antibiotics) to improve recovery and reduce complications.

Short name

Pneumococcal Serotype Test

Frequently asked questions

What does this test measure?
This test measures the presence of specific genetic material (DNA) from different serotypes of *Streptococcus pneumoniae* bacteria in your sample.
How long does it take to get results?
Results are usually available within 24 to 48 hours, depending on lab processing times.
Can I take anything special before this test?
No special preparation is needed, but follow your doctor’s instructions for sample collection (e.g., avoiding cough suppressants if using a nasal swab).
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy