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Staphylococcus aureus Detection by Polymerase Chain Reaction (PCR) in Blood

Published: August 9, 2026Updated: August 16, 2026

This test checks for the presence of *Staphylococcus aureus*, a common bacteria that can cause infections in the bloodstream, such as sepsis or bloodstream infections.

Quick summary

["This test helps doctors identify if bacteria are causing an infection in your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
74748-5
Short code
Deprecated Staph sp tuf Bld Pos Ql Prb Mag
Synonyms
Deprecated Staph sp tuf Bld Pos Ql Prb Mag
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-mag-capture
CPT
85610
SNOMED
396252006
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms like fever, chills, rapid heartbeat, or signs of infection (such as redness, pain, or swelling at a wound). It’s also used in patients who have undergone surgeries, medical devices (like catheters), or have weakened immune systems. This test helps quickly determine if bacteria like *Staphylococcus aureus* are responsible for your symptoms.

How the Test Works

A small sample of your blood is taken and sent to a lab. The lab uses a special technique called **polymerase chain reaction (PCR)** to detect genetic material from *Staphylococcus aureus*. This method is highly sensitive and can detect even very small amounts of bacteria.

What to Expect Before the Test

No special preparation is needed for this test. You may have a small needle inserted into a vein (usually in your arm) to draw blood. You might feel a slight pinch or discomfort, but it usually doesn’t take long. If you’re on blood-thinning medication, let your doctor know before the test.

What to Expect During the Test

The blood sample is processed in a lab where technicians analyze it for bacterial DNA. Results are typically available within a few days, depending on lab procedures. If the test is positive, it means *Staphylococcus aureus* was found in your blood.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: whole-blood

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

How long does it take to get the results of this test?
Results are usually available within 2 to 5 business days, depending on your lab’s processing schedule. Your doctor will contact you once the results are ready.
Can I eat or drink before this test?
No special diet or fasting is required for this test. You can eat and drink normally as usual.
What are the possible side effects of having blood drawn?
Most people experience only minor side effects, such as a small bruise, slight pain, or swelling at the injection site. Rarely, some people may feel lightheaded or dizzy, especially if they stand up too quickly after the blood is drawn.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy