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Timothy Grass-Specific IgG4 Antibody, Qualitative RAST (Deprecated)

Published: August 9, 2026Updated: August 17, 2026

A qualitative blood test that detects IgG4 antibodies directed toward Timothy grass, an allergen found in some grass pollens.

Quick summary

["This test can show prior exposure to Timothy grass, but it does not by itself diagnose a grass allergy."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
26431-7
Short code
Deprecated Timothy IgG4 RAST Ql
Synonyms
Deprecated Timothy IgG4 RAST Ql
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
10
Ref high
40
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84484
SNOMED
302774002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This test looks for IgG4 antibodies directed against Timothy grass in a blood sample, typically serum. These antibodies are part of the immune response to this grass allergen.

Why might I need this test?

It may be used to assess prior immune exposure to Timothy grass or to follow changes in the immune response to this allergen. It may also be relevant in some evaluations of allergen immunotherapy.

How is the test performed?

A laboratory uses a RAST-type method to determine whether Timothy grass-specific IgG4 is present. The result is reported qualitatively as detected or not detected rather than with a concentration value.

How do I prepare for the test?

No special preparation is usually required for a routine blood draw. Follow any instructions from the ordering clinician, particularly if the test is being tracked alongside allergy shots or other immunotherapy.

Reference range

Adult: 10-40 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Detected IgG4 antibodies generally indicate that the immune system has encountered Timothy grass, but this result alone does not establish a clinical allergy. The interpretation depends on symptoms, exposure history, and other allergy testing. Because this test is marked deprecated, a current testing option may be more appropriate.

Short name

Timothy grass IgG4 antibody test

Frequently asked questions

Does a positive result mean I am allergic to Timothy grass?
No. Detecting Timothy grass-specific IgG4 shows immune exposure and is not the same as demonstrating an allergic reaction. Allergy symptoms and other appropriate testing are needed to diagnose grass allergy.
How is this test different from a Timothy grass-specific IgE test?
This test measures IgG4 antibodies, while a specific IgE test measures antibodies more closely associated with immediate allergy reactions. Your clinician can explain which test is most useful for your situation.
Why is this test marked as deprecated?
The test may no longer be routinely ordered or available, or it may have been replaced by a more current method. Ask the ordering clinician whether an updated Timothy grass allergen test should be used instead.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy