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Vitamin C (Ascorbic Acid) in Serum or Plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of vitamin C, also called ascorbic acid, in your blood. Vitamin C is an essential nutrient that helps protect cells, supports immune function, and aids in wound healing.

Quick summary

["Check your vitamin C levels to ensure you’re getting enough of this important nutrient."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
6686-0
Short code
Deprecated Vit C SerPl-mCnc
Synonyms
Deprecated Vit C SerPl-mCnc
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order this test if you have symptoms of vitamin C deficiency, such as fatigue, frequent infections, or slow wound healing. It may also be used to monitor vitamin C levels in people taking supplements or those with conditions that affect nutrient absorption, like celiac disease or malabsorption syndromes.

Who Might Need This Test?

People at higher risk of vitamin C deficiency may undergo this test, including those with chronic illnesses, heavy smokers, individuals with certain dietary restrictions, or those undergoing chemotherapy. It may also be part of routine screening in specific clinical settings.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for a few hours before the blood draw if your doctor specifies it. Avoid taking vitamin C supplements 24 hours before the test, as this could affect results.

What Happens During the Test?

A healthcare provider will draw blood from a vein in your arm. The blood sample will be sent to a lab for analysis using a method like immunoassay or enzymatic techniques to measure vitamin C levels.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Low vitamin C levels may indicate deficiency, which can weaken immunity, cause scurvy-like symptoms, or worsen chronic conditions. High levels might suggest overconsumption of supplements or certain medical conditions. Results help guide treatment plans, such as adjusting dietary intake or supplement use.

Short name

Vitamin C Level

Frequently asked questions

What does a low vitamin C level mean?
A low vitamin C level may mean you’re not getting enough vitamin C through your diet or supplements. Your doctor may recommend dietary changes, increased intake of vitamin C-rich foods (like citrus fruits, bell peppers, or strawberries), or supplements if needed.
Can vitamin C supplements interfere with this test?
Yes, taking vitamin C supplements within 24 hours of your test could give you falsely high results. Your doctor may ask you to stop supplements temporarily or check with them before testing.
How often should I get this test?
The frequency depends on your health status. If you have a known deficiency or take supplements regularly, your doctor may recommend testing every few months. Otherwise, this test is usually not routine unless symptoms or risk factors arise.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy