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C-reactive protein (CRP) – Serum

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of C-reactive protein, a protein produced by the liver in response to inflammation in your body.

Quick summary

["CRP helps doctors assess inflammation, often used to monitor conditions like infections, autoimmune diseases, or heart disease."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
28000-8
Short code
Deprecated vWF Ag PPP EIA-aCnc
Synonyms
Deprecated vWF Ag PPP EIA-aCnc
Category
chemistry
Sample
plasma
Container
Lavender-top (EDTA) or Green-top (Heparin)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
eia
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is CRP Tested?

Doctors may order a CRP test to check for signs of inflammation, which can occur due to infections (like pneumonia or urinary tract infections), injuries, or certain medical conditions such as rheumatoid arthritis or heart disease. It can also help monitor how well treatments are working for these conditions.

What Does CRP Tell You?

Higher CRP levels often indicate inflammation. While CRP alone doesn’t diagnose a specific condition, it can guide further testing or treatment decisions. Very high levels might suggest severe infections or other serious health issues that need prompt attention.

How Is the Test Done?

A blood sample is taken from a vein, usually in your arm. The blood is sent to a lab where it is processed to measure CRP levels. The test typically takes a few hours to complete, and results are usually available within 24 hours.

What Are Common Results and What Do They Mean?

Results are usually reported in milligrams per liter (mg/L). A normal range can vary by lab, but generally, lower levels (often below 1 mg/L) suggest minimal inflammation. Moderate levels (1–3 mg/L) may indicate mild to moderate inflammation, while higher levels (above 3 mg/L) could signal more serious inflammation or infection.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

CRP

Frequently asked questions

What factors can affect CRP levels?
Several factors can influence CRP levels, including recent infections, injuries, smoking, stress, certain medications (like steroids), and underlying health conditions. For example, smoking can increase CRP levels, while regular physical activity may help lower them. Always discuss any changes in your health or lifestyle with your healthcare provider.
How often should I get a CRP test?
The frequency of CRP testing depends on your medical condition and why the test was ordered. Some people may need CRP tests regularly to monitor chronic conditions like heart disease or arthritis, while others may only need it once for diagnostic purposes. Follow your doctor’s recommendations.
Can CRP levels change over time?
Yes, CRP levels can fluctuate based on your health status, recent activities, and other factors. If you have a chronic condition, your doctor may retest CRP levels periodically to track changes and adjust treatment as needed. Avoiding stress, smoking, or heavy exercise before the test can help get a more accurate reading.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy