Deprecated Wasp Venom-Specific IgG4 Antibodies, Qualitative (RAST Method)
A qualitative blood test that detects IgG4 antibodies to wasp venom, indicating an immune response to prior exposure.
["A positive result shows wasp-venom exposure but does not by itself confirm a wasp-sting allergy."]
Key facts at a glance
- LOINC
- 26433-3
- Short code
- Deprecated Wasp Venom IgG4 RAST Ql
- Synonyms
- Deprecated Wasp Venom IgG4 RAST Ql
- Category
- liver
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 10
- Ref high
- 40
- Critical range
- — – 500 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 84484
- SNOMED
- 302774002
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What is this test?
This deprecated laboratory test looks for IgG4 antibodies directed against wasp venom. These antibodies are part of the immune response that can develop after exposure to wasp venom.
Why might I need this test?
It may have been used to document an immune response to wasp venom or to help evaluate possible exposure. It is not the same as testing for venom-specific IgE, which is more closely associated with an immediate allergic reaction.
How is the test performed?
A blood sample is analyzed using a laboratory immunoassay method known as RAST. The result is reported qualitatively as positive, negative, or possibly indeterminate, depending on the laboratory.
How do I prepare for the test?
No special preparation is usually required. Tell your clinician about any history of wasp stings, allergic reactions, or venom immunotherapy, because those details affect how the result should be interpreted.
Reference range
Adult: 10-40 U/LN/A
No special preparation required. Avoid fatty meals before the test if possible.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
A positive result indicates that IgG4 antibodies to wasp venom are present, which is consistent with prior exposure or an immune response. It does not prove that you have a clinical wasp-venom allergy, and these antibodies may also occur in people without allergic symptoms. A negative result does not rule out allergy or all forms of sensitization.
Short name
Wasp Venom IgG4 Antibodies
Frequently asked questions
Does a positive result mean I am allergic to wasps?
Why is this test marked as deprecated?
Can this test show whether venom immunotherapy is working?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy